The prevalence of epilepsy and other seizure disorders in an Arab population: a community-based study
The prevalence of epilepsy and other seizure disorders in an Arab population: a community-based study
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DOI：
10.1053/seiz.2001.0602
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发表时间：
2001-09-01
影响因子：
3
通讯作者：
Ogunniyi, A
中科院分区：
文献类型：
--
作者：
Al Rajeh, S;Awada, A;Ogunniyi, A
目的：确定沙特阿拉伯人群中癫痫和其他惊厥性疾病的患病率以及症状性癫痫的原因。方法：对23700名沙特国民居住的限定区域进行上门调查。世界卫生组织（世卫组织）旨在检测神经系统疾病的议定书被用作筛查工具。所有可能癫痫发作的患者都由神经科医生检查，92%的阳性病例进行了脑计算机断层扫描（CT）和脑电图（EEG）检查。结果：活动性癫痫患病率（PR）为6.54/ 1000（95%可信区间5.48 ~ 7.60）。28%的患者有部分癫痫发作。21%的全身性发作，51%的全身性发作无法确定是否有局灶性发作。32%的病例有癫痫症状：产前或围产期脑病23%，头部损伤4%，儿童神经系统感染4%，中风1%。6岁以下儿童的热性惊厥发生率为3.55/1000，单独惊厥发生率仅为0.18/1000。结论：沙特阿拉伯癫痫的PR在大多数社区报告的值范围内。症状性癫痫的病因以围产期和遗传因素为主。由于各种社会和文化因素以及问卷对非惊厥性发作缺乏敏感性，孤立性和非惊厥性发作可能未被充分认识。(C) 2001东亚贸易有限公司
Purpose: To determine the prevalence of epilepsy and other convulsive disorders and the causes of symptomatic epilepsies in a Saudi Arabian population.Methods: Door to door survey of a restricted area inhabited by 23 700 Saudi nationals. The World Health Organization (WHO) protocol designed to detect neurological disorders was used as screening instrument. All patients with probable seizures were examined by a neurologist and 92% of positive cases were investigated by brain computed tomography (CT) and electroencephalogram (EEG).Results: Prevalence rate (PR) for active epilepsy was 6.54/ 1000 population (95% confidence interval 5.48-7.60). Twenty-eight percent of the patients had partial seizures. 21% generalized seizures and in 51%, it was not possible to determine if the generalized seizures had focal onset or not. The epilepsy was symptomatic in 32% of the cases: pre or perinatal encephalopathy 23%, head injury 4%, childhood neurological infection 4% and stroke 1%. Febrile convulsions PR was 3.55/1000 children under the age of 6 years and isolated seizures were documented in only 0.18/1000 population.Conclusions: The PR of epilepsy in Saudi Arabs is within the range of the values reported in most communities. The causes of symptomatic epilepsies revealed a predominance of perinatal and inherited factors. Isolated and non-convulsive seizures were probably under-recognized due to various social and cultural factors as well as to lack of sensitivity of the questionnaire for non-convulsive seizures. (C) 2001 BEA Trading Ltd.