CLINICAL EFFICACY OF THE PULSED DYE-LASER IN THE TREATMENT OF VASCULAR-LESIONS
CLINICAL EFFICACY OF THE PULSED DYE-LASER IN THE TREATMENT OF VASCULAR-LESIONS
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DOI：
10.1111/j.1524-4725.1993.tb00353.x
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发表时间：
1993-04-01
期刊：
影响因子：
--
通讯作者：
BAKUS, AD
中科院分区：
文献类型：
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作者：
GARDEN, JM;BAKUS, AD
背景资料。提高激光损伤的选择性是激光治疗皮肤损伤的持续目标。闪光灯泵浦的脉冲染料激光器极大地参与并推动了这一追求。目的对激光治疗皮肤血管病变的发展和应用现状进行综述。方法：该激光的设计目的是限制激光的能量吸收和对血红蛋白和血管的损伤。这是通过设置波长在577到585 nm，脉冲持续时间在360到450毫秒。结果几乎所有类型的浅表小血管病变的治疗结果都是有益的，无论病变解剖部位或患者年龄。这些病变包括葡萄酒色斑、毛细血管扩张、毛细血管瘤和其他血管瘤和血管扩张。较深的皮肤血管突起和下肢毛细血管扩张已被证明对治疗反应较差。与以前使用的激光系统相比，增加的血管选择性使得不良反应大大减少。结论：基于数千次治疗和随访评估，脉冲染料激光似乎在治疗皮肤血管病变方面具有最大的安全边际，特别是对儿科人群。
BACKGROUND. Increasing the selectivity of laser-induced damage is an ongoing goal for the laser treatment of cutaneous lesions. The flashlamp-pumped pulsed dye laser has significantly participated and advanced this pursuit. This is especially true in its use for the treatment of cutaneous vascular lesions.OBJECTIVE. A review of the development and current use of this laser for the treatment of cutaneous vascular lesions will be presented.METHODS. The laser has been designed to limit laser energy absorption and damage to hemoglobin and the blood vessel. This has been done by setting the wavelength at 577 to 585 nm and the pulse duration at 360 to 450 museconds.RESULTS. The therapeutic results have been beneficial for almost all types of superficial small vessel vascular lesions regardless of lesional anatomic site or patient age. These lesions include port-wine stains, telangiectasia, capillary hemangioma, and other angiomata and vascular ectasia. Deeper cutaneous vascular processes and lower extremity telangiectases have proven to be less responsive to therapy. The increased vascular selectivity has allowed for a dramatic decrease in adverse effects when compared to previously used laser systems.CONCLUSION. Based on many thousands of treatment sessions and follow-up evaluation, the pulsed dye laser appears to have the greatest margin of safety in the treatment of cutaneous vascular lesions, especially for the pediatric populations.