Ocular manifestations of HIV infection/AIDS in South Indian patients

Ocular manifestations of HIV infection/AIDS in South Indian patients
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南印度患者 HIV 感染/艾滋病的眼部表现

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发表时间：
1999
期刊：
影响因子：
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通讯作者：
C. Rajalakshmi
C. Rajalakshmi
中科院分区：
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文献类型：
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作者：
D. Sahu;P. Namperumalsamy;P. Walimbe;C. Rajalakshmi

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目的：评估一组来自印度南部的人类免疫缺陷病毒(HIV)感染/获得性免疫缺陷综合征(AIDS)患者的眼部表现的性质和患病率，并阐述该疾病对现有卫生机构的影响。方法：对在本中心就诊的19例艾滋病患者(A组)进行检查。咨询后，对8名与患者有关系的人进行了HIV筛查，并对血清阳性者(B组)进行了眼部损害检查。结果：A组中HIV视网膜病变占34%，CMV视网膜病变占39%，单纯疱疹病毒相关性急性视网膜坏死和视网膜病变占11%，结节性脉络膜炎占11%，带状疱疹视网膜病变和疑似卡氏支原体脉络膜病变各占2.5%。B组筛查结果显示，其中6例(75%)无HIV血清阳性状态，无眼部症状。结论：HIV视网膜病变和机会性眼部感染在艾滋病患者中较为常见。异性恋是最常见的传播方式。由于没有现成的有效管理措施，通过适当咨询进行预防似乎是印度预防艾滋病的唯一办法。
Purpose: To evaluate the nature and prevalence of ocular manifestations in a group of patients with Human Immunodeficiency Virus (HIV) infection/Acquired Immunodeficiency Syndrome (AIDS) from South India, and to elaborate the impact of the disease on existing health agencies. Methods: We examined 19 consecutive patients with AIDS (Group-A) who presented to our centre. After counselling, HIV screening tests were also performed on 8 individuals related to the patients and those who were seropositive (Group-B) were examined for ophthalmic lesions. Results:In Group-A, HIV retinopathy was present in 34%, CMV retinitis in 39%, Herpes Simplex-related Acute Retinal Necrosis (ARN) and retinitis in 11%, tubercular choroiditis in 11%, while Herpes Zoster retinitis and presumed P. carinii choroidopathy each were observed in 2.5% of the eyes. Results of screening tests in Group-B revealed HIV-seropositive asymptomatic status in 6 (75%) of them with no ocular manifestations. Conclusion: HIV retinopathy and opportuninstic ocular infections were common in AIDS patients. Heterosexuality was the most common mode of transmission. Since no effective management is readily available, prevention through proper counselling appears to be the only defence against AIDS in India.