Multi-phase Liver Tumor Segmentation with Spatial Aggregation and Uncertain Region Inpainting
Multi-phase Liver Tumor Segmentation with Spatial Aggregation and Uncertain Region Inpainting
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DOI:
10.1007/978-3-030-87193-2_7
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发表时间:
2021-08
期刊:
影响因子:
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通讯作者:
Yue Zhang;Chengtao Peng;Liying Peng;Huimin Huang;Ruofeng Tong;Lanfen Lin;Jingsong Li;Yenwei Chen;Qingqing Chen;Hongjie Hu;Zhiyi Peng
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文献类型:
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作者:
Yue Zhang;Chengtao Peng;Liying Peng;Huimin Huang;Ruofeng Tong;Lanfen Lin;Jingsong Li;Yenwei Chen;Qingqing Chen;Hongjie Hu;Zhiyi Peng
Multi-phase computed tomography (CT) images provide crucial complementary information for accurate liver tumor segmentation (LiTS). State-of-the-art multi-phase LiTS methods usually fused cross-phase features through phase-weighted summation or channel-attention based concatenation. However, these methods ignored the spatial (pixel-wise) relationships between different phases, hence leading to insufficient feature integration. In addition, the performance of existing methods remains subject to the uncertainty in segmentation, which is particularly acute in tumor boundary regions. In this work, we propose a novel LiTS method to adequately aggregate multi-phase information and refine uncertain region segmentation. To this end, we introduce a spatial aggregation module (SAM), which encourages per-pixel interactions between different phases, to make full use of cross-phase information. Moreover, we devise an uncertain region inpainting module (URIM) to refine uncertain pixels using neighboring discriminative features. Experiments on an in-house multi-phase CT dataset of focal liver lesions (MPCT-FLLs) demonstrate that our method achieves promising liver tumor segmentation and outperforms state-of-the-arts.