Frequent importation of enterovirus 71 from surrounding countries into the local community of Yamagata, Japan, between 1998 and 2003
Frequent importation of enterovirus 71 from surrounding countries into the local community of Yamagata, Japan, between 1998 and 2003
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DOI：
10.1128/jcm.43.12.6171-6175.2005
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发表时间：
2005-12-01
影响因子：
9.4
通讯作者：
Hayasaka, K
中科院分区：
文献类型：
--
作者：
Mizuta, K;Abiko, C;Hayasaka, K
对日本山形地区6年来的45株肠道病毒71型(EV71)分离株的系统发育分析表明，每年手足口病的暴发是由四个遗传上截然不同的亚群引起的，其中包括一个新的B5亚群。我们的结果表明，从周边国家输入EV71对我们研究中使用的当地社区产生了重大的流行病学影响。
Phylogenetic analysis of 45 enterovirus 71 (EV71) isolates for 6 years in Yamagata, Japan, clarified that the annual outbreak of hand-foot-and-mouth disease was due to four genetically distinct subgenogroups, including a novel "B5." Our results suggest that the importation of EV71 from surrounding countries has had a major epidemiological impact on the local community used in our study.