Is There a High-Risk Subtype of Depression in Patients with Coronary Heart Disease?
Is There a High-Risk Subtype of Depression in Patients with Coronary Heart Disease?
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DOI：
10.1007/s11920-011-0247-6
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发表时间：
2012-02-01
影响因子：
6.7
通讯作者：
Freedland, Kenneth E.
中科院分区：
文献类型：
--
作者：
Carney, Robert M.;Freedland, Kenneth E.
抑郁症是冠心病患者心脏发病率和死亡率的危险因素，特别是在那些最近有急性冠脉综合征病史的患者中。为了改进风险分层和治疗计划，确定与心脏事件最高风险相关的抑郁症的特征或亚型将是有用的。本文综述了几种可能与心脏病患者发病率和死亡率高风险相关的抑郁症亚型和症状模式的证据，包括单发重度抑郁障碍、心脏事件后出现的抑郁、抑郁的躯体症状和治疗耐药抑郁。
Depression is a risk factor for cardiac morbidity and mortality in patients with coronary heart disease, especially in those with a recent history of acute coronary syndrome. To improve risk stratification and treatment planning, it would be useful to identify the characteristics or subtypes of depression that are associated with the highest risk of cardiac events. This paper reviews the evidence concerning several putative depression subtypes and symptom patterns that may be associated with a high risk of morbidity and mortality in cardiac patients, including single-episode major depressive disorder, depression that emerges after a cardiac event, somatic symptoms of depression, and treatment-resistant depression.