ORDINAL POSITION AND AFFERENT INPUT OF NEURONS IN MONKEY STRIATE CORTEX
ORDINAL POSITION AND AFFERENT INPUT OF NEURONS IN MONKEY STRIATE CORTEX
复制标题
DOI：
10.1002/cne.901930407
复制
发表时间：
1980-01-01
影响因子：
2.5
通讯作者：
HENRY, GH
中科院分区：
文献类型：
--
作者：
BULLIER, J;HENRY, GH
根据猴[Macaca nemestrina]纹状体皮质中单个单位的细胞外记录和视辐射中2个选定部位的电刺激，可以估计纹状体神经元的顺序位置（即，它们是否从丘脑接收单突触、双突触或多突触输入）和对这些神经元的传入输入的性质（即，是否来自外侧膝状体核（LGN）的大细胞或小细胞亚群）。根据感受野的特性，我们将纹状体神经元分为6大类：3类缺乏定向特异性（ON-中心、OFF-中心和ON/OFF或无定向（N-0）感受野），3类具有定向特异性反应（S、C和B类感受野）。缺乏取向特异性的单元集中在层4A、4C β中。和6.对于具有定向特异性的细胞，在第4层B和第6层中发现C细胞，在第2/3层和第5层中发现B细胞，而在第2/3层、第4 C α层中主要发现S细胞。和5.电刺激表明，细胞间的传输时间在猴子的纹状体皮层为1.5毫秒。潜伏期的措施表明，从丘脑单突触驱动的细胞被限制在第4和第6层，双突触驱动的细胞主要被发现在上层4（4A和4 B）。没有细胞类别被确定专门与一个给定的顺序位置，有许多类型的潜在的第一阶神经元。视辐射中从一个刺激电极到下一个刺激电极的传导时间用于识别每个纹状体神经元的传入输入。彩色编码神经元的输入完全来自小细胞层。C细胞和S细胞的2个亚类（S2和S3）主要由大细胞亚群驱动。对于其他类型的细胞（具有ON中心、N-0和S1感受野的细胞），输入来自任一类型的LGN神经元。从大细胞和小细胞流接收直接输入的神经元的层状分布与LGN输入终止部位的解剖学相关。接收这些直接输入的细胞类型在2个流中不同，使得小细胞输入终止于在板层4C β中具有ON-中心和N-0感受野的细胞上。大细胞输入到达在层4C α中具有S、ON-中心、N-0和C感受野的细胞。和4 B的下部。模型的神经处理在猴子的纹状体皮层被认为是与猫的比较。
From the extracellular recording of single units in the monkey [Macaca nemestrina] striate cortex and electrical stimulation at 2 selected sites in the optic radiations it was possible to estimate the ordinal position of striate neurons (i.e., whether they received a monosynaptic, disynaptic or polysynaptic input from the thalamus) and the nature of the afferent input to these neurons (i.e., whether it came from the magnocellular or parvocellular subdivision of the lateral geniculate nucleus (LGN)). Based on receptive field properties 6 major classes of striate neuron were identified: 3 classes lacked orientation specificity (the ON-center, the OFF-center and the ON/OFF or nonoriented (N-0) receptive fields) and 3 classes showed orientation specific responses (the S, C and B categories of receptive field). Units lacking orientation specificity were concentrated in laminae 4A, 4C.beta. and 6. For the cells with orientation specificity, C cells were found in laminae 4B and 6, B cells occurred in 2/3 and 5, and S cells occurred predominantly in laminae 2/3, 4C.alpha. and 5. Electrical stimulation indicated that cell-to-cell transmission time in the monkey striate cortex was 1.5 ms. Latency measures showed that cells with a monosynaptic drive from the thalamus were confined to laminae 4 and 6; disynaptically driven cells were found principally in upper lamina 4 (4A and 4B). No cell class was identified exclusively with a given ordinal position and there were many types of potential 1st-order neurons. The conduction time from 1 stimulating electrode to the next in the optic radiation was used to identify the afferent input to each striate neuron. The input to color-coded neurons was exclusively from parvocellular layers. The C cells and 2 subclasses of the S cell (S2 and S3) were driven predominantly by the magnocellular subdivision. For other cell types (those with ON-center, N-0 and S1 receptive fields) the input came from either type of LGN neuron. The laminar distribution of neurons receiving a direct input from the magnocellular and parvocellular streams correlates with the anatomy into the site of termination of the LGN input. The cell types receiving these direct inputs vary in the 2 streams so that the parvocellular input terminates on cells with ON-center and N-0 receptive fields in lamina 4C.beta.. The magnocellular input goes to cells with S, ON-center, N-0 and C receptive fields in lamina 4C.alpha. and the lower part of 4B. Models for neural processing in monkey striate cortex are considered and a comparison with the cat is drawn.