Ozone modifies associations between temperature and cardiovascular mortality: analysis of the NMMAPS data
Ozone modifies associations between temperature and cardiovascular mortality: analysis of the NMMAPS data
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DOI：
10.1136/oem.2007.033878
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发表时间：
2008-04-01
影响因子：
4.9
通讯作者：
Tong, S.
中科院分区：
文献类型：
--
作者：
Ren, C.;Williams, G. M.;Tong, S.
目的：环境臭氧和温度都与人类健康有关。然而，关于臭氧是否会改变温度效应的数据很少。本研究的目的是探讨臭氧是否修改之间的关联最高温度和心血管疾病死亡率在USA.Methods：作者从美国国家发病率，死亡率和空气污染研究（NMMAPS）网站获得的数据。他们使用两个时间序列泊松回归模型（响应面模型和分层模型）来研究臭氧是否改变了1987-2000年夏季（6月至9月）美国95个大型社区的最高温度和心血管死亡率（CVM）之间的关联。结果：利用响应面模型分析了夏季温度和臭氧对CVM的联合影响。结果表明，臭氧积极修改的温度CVM协会在不同地区。分层模型量化的温度CVM协会在不同层次的臭氧。结果表明，一般来说，臭氧浓度越高，越强的温度CVM协会在整个社区。在同一天的温度增加10摄氏度与CVM增加1.17%和8.31%的最低和最高水平的臭氧浓度在所有community.Conclusion：臭氧改性温度在美国不同地区的影响。在估计与温度有关的健康影响时，必须评估臭氧的改变作用，并进一步调查区域变异性背后的原因和温度与臭氧之间相互作用的机制。
Objectives: Both ambient ozone and temperature are associated with human health. However, few data are available on whether ozone modifies temperature effects. This study aims to explore whether ozone modified associations between maximum temperature and cardiovascular mortality in the USA.Methods: The authors obtained data from the US National Morbidity, Mortality, and Air Pollution Study (NMMAPS) website. They used two time-series Poisson regression models (a response surface model and a stratification model) to examine whether ozone modified associations between maximum temperature and cardiovascular mortality (CVM) in 95 large US communities during 1987-2000 in summer (June to September). Bayesian meta-analysis was used to pool estimates in each community.Results: The response surface model was used to examine the joint effects of temperature and ozone on CVM in summer. Results indicate that ozone positively modified the temperature-CVM associations across the different regions. The stratification model quantified the temperature-CVM associations across different levels of ozone. Results show that in general the higher the ozone concentration, the stronger the temperature-CVM associations across the communities. A 10 degrees C increase in temperature on the same day was associated with an increase in CVM by 1.17% and 8.31% for the lowest and highest level of ozone concentrations in all communities, respectively.Conclusion: Ozone modified temperature effects in different regions in the USA. It is important to evaluate the modifying role of ozone when estimating temperature-related health impacts and to further investigate the reasons behind the regional variability and mechanism for the interaction between temperature and ozone.