Fish consumption is inversely associated with the metabolic syndrome
Fish consumption is inversely associated with the metabolic syndrome
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DOI：
10.1038/ejcn.2014.5
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发表时间：
2014-04-01
影响因子：
4.7
通讯作者：
Esmaillzadeh, A.
中科院分区：
文献类型：
--
作者：
Zaribaf, F.;Falahi, E.;Esmaillzadeh, A.
背景/目的：虽然鱼类消费与几种代谢异常呈负相关，但有限且不一致的数据报告了鱼类消费与代谢综合征之间的关系。本研究的目的是确定鱼类消费和代谢综合征及其组件之间的关联SUBJECTS/METHODS：在一项横断面研究中进行了420名伊朗女性成年人，通常的鱼类消费进行了评估，使用一个菜为基础的半定量食物频率问卷（FFQ）。采集空腹血样进行生化评估。根据标准方案进行人体测量和血压测量。代谢综合征的定义基于国家胆固醇教育计划成人治疗小组III指南。多变量logistic回归调整生活方式和饮食变量，以评估鱼类代谢综合征association.Results：代谢综合征的患病率为8.2%。鱼的平均日摄入量为14.4克/天。鱼类摄入量最高的三分位数的个体患代谢综合征的可能性比最低的三分位数的个体低65%（比值比：0.35; 95%置信区间（CI）：0.14-0.88）。控制潜在的混杂因素和饮食变量加强了这种关联（优势比：0.05; 95%CI：0.004-0.64）。在调整了潜在的共同因素后，高鱼类摄入量与高胆固醇血症呈负相关（比值比：0.11; 95% CI：0.01-0.85），低高密度脂蛋白胆固醇（比值比：0.57; 95% CI：0.19-0.89）和血压升高结论：我们发现鱼类摄入量的增加与代谢综合征及其特征的低风险独立相关。需要进一步的前瞻性研究来证实这种关联。
BACKGROUND/OBJECTIVES: Although fish consumption has inversely been associated with several metabolic abnormalities, limited and inconsistent data have reported the relationship between fish consumption and metabolic syndrome. The aim of this study was to identify the association between fish consumption and metabolic syndrome and its components.SUBJECTS/METHODS: In a cross-sectional study conducted on 420 Iranian female adults, usual fish consumption was assessed using a dish-based semiquantitative food frequency questionnaire (FFQ). Fasting blood samples were taken for biochemical assessment. Anthropometric and blood pressure measurements were carried out according to standard protocols. Metabolic syndrome was defined based on the National Cholesterol Education Program Adult Treatment Panel III guidelines. Multivariate logistic regression adjusted for lifestyle and dietary variables was applied to assess fish-metabolic syndrome association.RESULTS: The prevalence of metabolic syndrome was 8.2%. Mean daily intake of fish was 14.4 g per day. Individuals in the highest tertile of fish intake were 65% less likely to have the metabolic syndrome than those in the lowest tertile (odds ratio: 0.35; 95% confidence interval (CI): 0.14-0.88). Controlling for potential confounders and dietary variables strengthened this association (odds ratio: 0.05; 95% CI: 0.004-0.64). After adjustment for potential cofounders, high fish intake was inversely associated with hypertriglyceridemia (odds ratio: 0.11; 95% CI: 0.01-0.85), low high-density lipoprotein cholesterol (odds ratio: 0.57; 95% CI: 0.19-0.89) and elevated blood pressure (odds ratio: 0.23; 95% CI: 0.14-0.89).CONCLUSIONS: We found that increased fish intake was independently related to the lower odds of metabolic syndrome and its features. Further prospective investigations are warranted to confirm this association.