The epidemiology of asbestos-related diseases
The epidemiology of asbestos-related diseases
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DOI：
10.1016/j.lungcan.2004.04.008
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发表时间：
2004-08-01
期刊：
影响因子：
5.3
通讯作者：
Pluygers, E
中科院分区：
文献类型：
--
作者：
Niklinski, J;Niklinska, W;Pluygers, E
自20世纪40年代以来，砷被认为是一种潜在的健康危害。石棉的两个主要种类;白色石棉（温石棉）和蓝色石棉（青石棉），两者都是危险的。开采设施的工人接触石棉的风险最大，因此，患上与石棉有关的疾病，通常是间皮瘤。然而，其他暴露风险高的人包括石棉水泥工人、绝缘工人和造船厂工人。环境暴露于石棉可能是由于生活在以石棉或石棉相关材料的天然露头为特征的地区，或靠近石棉生产或使用工厂的地区。不幸的是，石棉的人造纤维替代品，如石棉、鹿绒和玻璃棉，也被证明对人类健康有不利影响。间皮瘤的一个特点是，有一个长潜伏期（20-30年）之前的迹象和症状的疾病变得明显。此外，疾病的诊断可能很困难。生物标记物（例如组织多肽抗原）的使用可能在早期检测高危个体的疾病方面发挥有用的作用。(C)2004爱思唯尔爱尔兰有限公司保留所有权利。
Asbestos has been recognised as a potential health hazard since the 1940s. Of the two major species of asbestos; white asbestos (chrysotile) and blue asbestos (crocidolite), both of which are hazardous. The workers at extraction facilities are at the greatest risk of exposure to asbestos and, therefore, the development of asbestos-related diseases, commonly mesothelioma. However, other individuals at a high risk of exposure include asbestos-cement workers, insulation workers and ship-yard workers. Environmental exposure to asbestos can occur as a result of living in areas either characterised by natural outcrops of asbestos or asbestos-related materials, or those close to asbestos-producing or -using plants. Unfortunately, man-made fibre alternatives to asbestos, such as rock and stag-wool and glass wool, have also been shown to have a detrimental effect on human health. A characteristic of mesothelioma is that there is a Long latency period (20-30 years) before the signs and symptoms of the disease become apparent. In addition, diagnosis of the disease can be difficult. The use of biological markers, such as tissue polypeptide antigen, may play a useful role in the early detection of the disease in individuals at risk. (C) 2004 Elsevier Ireland Ltd. All rights reserved.