Lack of Evidence for Frequent Heterosexual Transmission of Human Herpesvirus 8 in Zimbabwe
Lack of Evidence for Frequent Heterosexual Transmission of Human Herpesvirus 8 in Zimbabwe
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DOI：
10.1086/598978
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发表时间：
2009-06-01
影响因子：
11.8
通讯作者：
Gwanzura, Lovemore
中科院分区：
文献类型：
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作者：
Campbell, Thomas B.;Borok, Margaret;Gwanzura, Lovemore
背景关于异性传播对人类疱疹病毒8型（HHV-8）在南部非洲传播的贡献，存在相互矛盾的证据。本研究评估了HHV-8感染与津巴布韦男性中人类免疫缺陷病毒1型（HIV-1）和其他性传播感染的危险因素相关的假设。在津巴布韦哈拉雷的津巴布韦艾滋病预防项目男性工厂工人队列中，确定了2750名参与者的HHV-8血清阳性率。单因素分析HHV-8抗体检测与HIV-1感染危险因素的潜在关联。变量P
Background. There is conflicting evidence about the contribution of heterosexual transmission to the spread of human herpesvirus 8 (HHV-8) in southern Africa. This study evaluated the hypothesis that HHV-8 infection is associated with risk factors for human immunodeficiency virus type 1 (HIV-1) and other sexually transmitted infections among Zimbabwean men.Methods. HHV-8 seroprevalence was determined for 2750 participants in the Zimbabwe AIDS Prevention Project cohort of male factory workers in Harare, Zimbabwe. Potential associations of HHV-8 antibody detection with risk factors for HIV-1 infection were examined by univariate analysis. Variables with P