Parahydrogen-induced polarization in imaging:: Subsecond 13C angiography
Parahydrogen-induced polarization in imaging:: Subsecond 13C angiography
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DOI：
10.1002/mrm.1152
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发表时间：
2001-07-01
影响因子：
3.3
通讯作者：
Petersson, JS
中科院分区：
文献类型：
--
作者：
Golman, K;Axelsson, O;Petersson, JS
有机分子中达到了 C-13 的高核自旋极化。与 1.5 T 的热极化相比，使用仲氢诱导极化技术与场循环方法相结合，可实现高达 10(4) 的增强。虽然仲氢没有净极化，但它具有高自旋序，当氢通过化学反应结合到另一个分子中时，它会保留下来。通过使该分子受到外部磁场的突然变化，自旋顺序转变为净极化。不到一秒即可生成动物的 C-13 血管造影照片。 (C) 2001 Wiley-Liss, Inc.
High nuclear spin polarization of C-13 was reached in organic molecules. Enhancements of up to 10(4), compared to thermal polarization at 1.5 T, were achieved using the parahydrogen-induced polarization technique in combination with a field cycling method. While parahydrogen has no net polarization, it has a high spin order, which is retained when hydrogen is incorporated into another molecule by a chemical reaction. By subjecting this molecule to a sudden change of the external magnetic field, the spin order is transferred into net polarization. A C-13 angiogram of an animal was generated in less than a second. (C) 2001 Wiley-Liss, Inc.