The psychosocial context impacts medication adherence after acute coronary syndrome.
The psychosocial context impacts medication adherence after acute coronary syndrome.
复制标题
DOI：
10.1007/s12160-013-9544-0
复制
发表时间：
2014-04
影响因子：
3.8
通讯作者：
Davidson, Karina W.
中科院分区：
文献类型：
--
作者：
Kronish, Ian M.;Rieckmann, Nina;Burg, Matthew M.;Alcantara, Carmela;Davidson, Karina W.
抑郁症与急性冠脉综合征（ACS）患者的药物依从性差和预后不良有关。确定抑郁症的认知、行为和/或心理社会脆弱性是否可以解释ACS患者抑郁症与药物依从性之间的关系。169名同意使用电子药瓶测量阿司匹林依从性3个月的ACS患者在住院后1周内入组。在调整抑郁症状、人口统计学和合并症后，采用线性回归确定抑郁易感性是否预测阿司匹林的依从性。在抑郁脆弱性中，只有角色转换（beta =-3.32; p=0.02）和人际冲突（beta =-3.78; p=0.03）预测了较差的依从性。抑郁症的脆弱性并没有调解抑郁症状和药物依从性之间的关联。ACS发生前的心理社会背景的关键因素包括主要角色转换和与密切接触者的冲突，这些因素使ACS患者的药物依从性差的风险增加，而与抑郁症状无关。
Depression is associated with poor adherence to medications and worse prognosis in patients with acute coronary syndrome (ACS). To determine whether cognitive, behavioral, and/or psychosocial vulnerabilities for depression explain the association between depression and medication adherence among ACS patients. 169 ACS patients who agreed to have their aspirin adherence measured using an electronic pill bottle for 3 months were enrolled within 1 week of hospitalization. Linear regression was used to determine whether depression vulnerabilities predicted aspirin adherence after adjustment for depressive symptoms, demographics, and comorbidity. Of the depression vulnerabilities, only role transitions (beta = −3.32; p=0.02) and interpersonal conflict (beta −3.78; p=0.03) predicted poor adherence. Depression vulnerabilities did not mediate the association between depressive symptoms and medication adherence. Key elements of the psychosocial context preceding the ACS including major role transitions and conflict with close contacts place ACS patients at increased risk for poor medication adherence independent of depressive symptoms.
登录
查看更多内容
影响因子：
3.3
作者：
Phillips, L. Alison;Leventhal, Howard;Leventhal, Elaine A.
通讯作者：
Leventhal, Elaine A.
影响因子：
2.8
作者：
Bolman, Catherine;Arwert, Titia G.;Vollink, Trijntje
通讯作者：
Vollink, Trijntje
影响因子：
--
作者：
DiMatteo, MR;Lepper, HS;Croghan, TW
通讯作者：
Croghan, TW
DOI：
10.3758/bf03206553
发表时间：
2004-11-01
期刊：
BEHAVIOR RESEARCH METHODS INSTRUMENTS & COMPUTERS
影响因子：
--
作者：
Preacher, KJ;Hayes, AF
通讯作者：
Hayes, AF
影响因子：
4.8
作者：
Kronish, Ian M.;Rieckmann, Nina;Davidson, Karina W.
通讯作者：
Davidson, Karina W.