CHANGE OF RESIDUAL STRAINS IN ARTERIES DUE TO HYPERTROPHY CAUSED BY AORTIC CONSTRICTION
CHANGE OF RESIDUAL STRAINS IN ARTERIES DUE TO HYPERTROPHY CAUSED BY AORTIC CONSTRICTION
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DOI：
10.1161/01.res.65.5.1340
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发表时间：
1989-11-01
影响因子：
20.1
通讯作者：
LIU, SQ
中科院分区：
文献类型：
--
作者：
FUNG, YC;LIU, SQ
当外部载荷被移除时，残留在器官中的应力和应变被称为残余应力和应变。它们可以通过切割器官来显示，以便显示零应力配置。器官的功能取决于残余应变。对于血管，零应力配置与无负载条件下的配置非常不同，并且当作用在血管上的物理应力改变时，零应力配置随时间而改变。提供了大鼠主动脉的数据。 通过用金属带在腹腔干水平收缩主动脉来获得物理变化。带状引起上半身血压升高和血管肥大，下半身血压短暂降低。如果主动脉被横向切割成环，每个环被径向切割，它将打开成一个非圆弧，这可以通过它的开口角来表征。结果表明，主动脉张开角沿主动脉沿着呈系统性变化，并随血压和肥厚的变化而显著变化。在升主动脉中，张开角从171 °增加。214度。在绑扎后4天，然后逐渐降低到126 °的渐近值。在40天内。在其它截面上，开度角的摆动较小。的影响进行了讨论。
The stress and strain that remain in an organ when the external load is removed are called residual stress and strain. They can be revealed by cutting up the organ in such a way as to reveal the zero-stress configuration. The function of the organ depends on the residual strain. For a blood vessel, the zero-stress configuration is very different from that of the no-load condition, and it changes over time when the physical stress acting on the vessel is changed. Data on rat aorta is presented. Physical changes were obtained by constricting the aorta at the celiac trunk level with a band of metal. Banding causes an increase of blood pressure and hypertrophy of the vessel in the upper body and a transient decrease of blood pressure in the lower body. If the aorta is cut transversely into rings and each ring is cut radially, it will open up into a noncircular arc, which may be characterized by its opening angle. It is shown that the opening angle varies systematically along the aorta and that it changes significantly together with changes of blood pressure and hypertrophy. In the ascending aorta, the opening angle increased from 171.degree. and to 214.degree. in 4 days after banding, then decreased gradually to an asymptotic value of 126.degree. in 40 days. At other sections, the swing of opening angle is smaller. The implications are discussed.