Differences in pHi recovery in CO2-chemosensitive and non-chemosensitive cells: predictions from a mathematical model.
Differences in pHi recovery in CO2-chemosensitive and non-chemosensitive cells: predictions from a mathematical model.
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CO2 化学敏感细胞和非化学敏感细胞中 pHi 恢复的差异：数学模型的预测。
DOI：
10.1109/iembs.2006.260895
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发表时间：
2006
期刊：
影响因子：
--
通讯作者：
Solomon,IreneC
中科院分区：
文献类型：
--
作者：
Cordovez,JuanM;Clausen,Chris;Moore,LeonC;Solomon,IreneC
在本文中，我们提出了一个数学模型，旨在确定潜在的机制，负责观察到的差异，pHi恢复在CO2化学敏感性与非化学敏感性细胞。该模型表明，pH调节的差异可能取决于Na+/H+交换器（NHE）的内部改性剂位点的活化设定点的差异。
in this paper, we present a mathematic model designed to identify potential mechanisms responsible for the observed differences in pHi recovery in CO2-chemosensitive versus non-chemosensitive cells. The model suggests that differences in pHi regulation may be dependent upon differences in the activation set-point of the internal modifier site of the Na+/H+ exchanger (NHE).