A case of contrast-induced pancreatitis following cardiac catheterization.
A case of contrast-induced pancreatitis following cardiac catheterization.
复制标题
心导管插入术后造影剂诱发胰腺炎一例。
DOI：
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发表时间：
2013
期刊：
影响因子：
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通讯作者：
Marcel Zughaib
中科院分区：
文献类型：
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作者：
R. Gorges;Wael Ghalayini;Marcel Zughaib
冠心病仍然是美国男性和女性死亡的主要原因。血管造影术和经皮冠状动脉介入治疗（PCI）是急性冠状动脉综合征管理中不可或缺的一部分。明确定义的冠状动脉造影术并发症包括过敏反应、血管通路并发症、卒中和造影剂诱导的肾损伤。已知放射造影剂（RCA）可引起急性肾损伤。RCA也被假定在实验动物模型中诱导胰腺炎。我们报告一位冠状动脉造影后立即发生急性胰脏炎的病例。最近的研究表明，RCA的使用与进行性胰腺炎患者的预后较差相关。RCA诱发胰腺炎的病理生理机制尚不清楚。虽然非常罕见，但RCA诱导的胰腺炎应在适当的临床环境中考虑。
Coronary heart disease remains the leading cause of death of men and women in the United States. Angiography and percutaneous coronary interventions (PCI) are an integral part in management of acute coronary syndromes. Well-defined complications of coronary angiography include allergic and anaphylactic reactions, vascular access complications, stroke, and contrast-induced kidney injury. Radiographic contrast agents (RCAs) are known to cause acute kidney injury. RCAs are also postulated to induce pancreatitis in experimental animal models. We present a patient with acute pancreatitis immediately following coronary angiography. Recent studies have described that the use of RCA is associated with worse prognosis in patients with ongoing pancreatitis. The pathophysiology of RCA-induced pancreatitis is poorly understood. Although extremely rare, RCA-induced pancreatitis should be considered in the appropriate clinical setting.