THE SAGITTAL VESTIBULOCOLLIC REFLEX AND ITS INTERACTION WITH NECK PROPRIOCEPTIVE AFFERENTS IN THE DECEREBRATE CAT
THE SAGITTAL VESTIBULOCOLLIC REFLEX AND ITS INTERACTION WITH NECK PROPRIOCEPTIVE AFFERENTS IN THE DECEREBRATE CAT
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DOI：
10.1113/jphysiol.1985.sp015572
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发表时间：
1985-01-01
影响因子：
5.5
通讯作者：
HUNTER, MJ
中科院分区：
文献类型：
--
作者：
DUTIA, MB;HUNTER, MJ
在去大脑猫上研究了头仰、头俯运动诱发的颈二腹伸肌矢状前庭反射（vcr）。头仰运动使左右侧颈二腹伸肌肌电活动增加，头仰运动使左右侧颈二腹伸肌肌电活动减少。在正弦头部运动的低频率（0.1- 0.5Hz），矢状面VCR的增益近似恒定，并且EMG调制显示相位超前40 °。相对于头部位置。在较高频率（2-5 Hz），VCR增益以接近40 dB/十倍的速率增加，相位超前增加到接近150 °。头部运动和VCR活动之间的关系可以用一个传递函数来描述，该传递函数包含两个超前项，时间常数为0.07和0.23 s，以及两个滞后项，时间常数为5.3和9.9 s。当头部的运动伴随着颈二腹肌的伸展时，矢状面VCR的增益增加了3倍，在0.1和5 Hz之间的所有频率下，相位没有实质性变化。在头部静止的情况下，正弦拉伸颈二腹肌，诱发牵张反射（颈结肠反射，CCR），其行为类似于由包含时间常数为0.07和0.16 s的2导联项的传递函数描述的2阶系统的行为。vcr和ccr之间的动力学差异表明，vcr传递函数中的滞后项反映了前庭通路到颈二腹肌的频率响应特性，因为当相同的肌肉参与ccr时，它们不会出现。矢状面vcr的频率响应之间的矢量差异，伴随和不伴随颈二腹肌的拉伸，在数量上类似于窦状面拉伸诱发的ccr的频率响应。因此，来自前庭和牵张感受器的输入似乎线性相加，以产生vcr增益的增加，至少在0.1- 1Hz的频率范围内。由于大多数头部运动，以及所有自主的头部运动，都涉及到头部相对于颈部的旋转，因此颈部肌肉中的牵张感受器（可能是肌梭）传入的vcr增益增强是头部位置正常反射稳定的重要因素。
The sagittal vestibulocollic reflex (vcr) evoked by nose-up, nose-down movements of the head, was studied in the neck extensor muscle biventer cervicis in the decerebrate cat. Nose-down movements of the head increased and nose-up movements decreased electromyographic (EMG) activity in the biventer cervicis muscles of the left and right sides. At low frequencies of sinusoidal head movement (0.1-0.5 Hz), the gain of the sagittal vcr was approximately constant, and EMG modulation showed a phase lead 40.degree. with respect to head position. At higher frequencies (2-5 Hz), vcr gain increased at a rate close to 40 dB/decades and phase lead increased to approach 150.degree.. The relation between head movement and vcr activity may be described by a transfer function containing 2 lead terms, with time constants of 0.07 and 0.23 s, and 2 lag terms, with time constants of 5.3 and 9.9 s. When movements of the head were accompanied by stretching of the biventer cervicis muscles, the gain of the sagittal vcr was increased 3-fold, at all frequencies between 0.1 and 5 Hz, with no substantial change in phase. Sinusoidal stretching of the biventer cervicis muscles, with the head stationary, evoked a stretch reflex (cervicocollic reflex, ccr) the behavior of which was similar to that of a 2nd-order system described by a transfer function containing 2 lead terms with time constants of 0.07 and 0.16 s. This difference in dynamics between the vcr and the ccr indicates that the lag terms in the vcr transfer function reflect the frequency-response properties of the vestibular pathway to the biventer cervicis muscles, as they do not appear when the same muscles participate in the ccr. The vectorial differences between the frequency-response of the sagittal vcr, with and without concomitant stretching of the biventer cervicis muscles is quantitatively similar to the frequency-response of the ccr evoked by sinousoidal stretching. The inputs from the vestibular and stretch receptors thus appear to sum linearly to produce the increase in vcr gain, at least over the frequency range 0.1-1 Hz. Since most head movements, and all voluntary head movements, involve a rotation of the head in relation to the neck, the potentiation of the gain of the vcr by afferents from stretch receptors (presumably muscle spindles) in the neck muscles is an important factor in the normal reflex stabilization of head position.