Contemplating genetic feedback regarding lung cancer susceptibility.
Contemplating genetic feedback regarding lung cancer susceptibility.
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考虑有关肺癌易感性的遗传反馈。
DOI：
10.1007/s12160-013-9561-z
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发表时间：
2014
期刊：
影响因子：
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通讯作者：
Lipkus,IsaacM
中科院分区：
文献类型：
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作者：
Shepperd,JamesA;Novell,CorinneA;O'Neill,SuzanneC;Docherty,SharronL;Sanderson,SaskiaC;McBride,ColleenM;Lipkus,IsaacM
Background and PurposeWe examined three theoretical models (self-enhancement theory, consistency theory, and a combined model) for understanding how expectations and test result favorability influence smokers’ desire for a retest following hypothetical genetic test results.MethodCollege smokers (N= 128) read a brochure describing a biomarker for lung cancer (theGSTM1gene) then reported whether they thought they had the gene (indicating lower lung cancer risk) or were missing the gene (indicating higher lung cancer risk). Participants then reported whether they would get retested if they received favorableGSTM1results versus unfavorableGSTM1results.ResultsParticipants were most likely to want a retest, suggesting rejection of the results, if they expected favorable news yet received unfavorable news.ConclusionThe findings supported the combined model such that smokers expressed greatest interest in a retest when they imagined genetic risk feedback that challenges both enhancement and consistency motives.
