The "beta-fluorine effect" in the non-metal hydride radical deoxygenation of fluorine-containing nucleoside xanthates.
The "beta-fluorine effect" in the non-metal hydride radical deoxygenation of fluorine-containing nucleoside xanthates.
复制标题
含氟核苷黄原酸盐非金属氢化物自由基脱氧中的“β-氟效应”。
DOI：
10.1080/15257770008032993
复制
发表时间：
2000
期刊：
影响因子：
--
通讯作者：
Marquez,VE
中科院分区：
文献类型：
--
作者：
Siddiqui,MA;Driscoll,JS;Abushanab,E;Kelley,JA;BarchiJr,JJ;Marquez,VE
An alternative method to conduct a Barton-McCombie deoxygenation in nucleosides is described. The utility of the procedure is limited to structures with an electronegative substituent, particularly fluorine, in the β-position relative to the radical center. The process is radical in nature and triggered by peroxides. The abstraction of hydrogen from the solvent is favorably influenced by the presence of a β-fluorine.
