Testing Pharmacological Profiles with Biomarkers Relevant to Cardiovascular Profiles
Testing Pharmacological Profiles with Biomarkers Relevant to Cardiovascular Profiles
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DOI：
10.1007/978-94-007-7678-4_27
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发表时间：
2016-01-01
期刊：
影响因子：
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通讯作者：
Maffioli, Pamela
中科院分区：
文献类型：
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作者：
Derosa, Giuseppe;Maffioli, Pamela
心血管疾病是美国和欧洲发病和死亡的主要原因。早期识别与心血管疾病相关的生物标志物可以有效识别高危患者并对其进行早期治疗，以减少心血管疾病的发生。本章的目的是检查与心血管疾病相关的生物标志物，以确定药物治疗可以发挥作用的目标。在本章中，我们将研究与心血管疾病相关的胰岛素抵抗、炎症、内皮损伤和代谢的主要标志物。
Cardiovascular diseases are the leading cause of morbidity and mortality in the United States and in Europe. Early identification of biomarkers linked to cardiovascular disease can be effective in identifying high-risk patients to early treat them in order to reduce cardiovascular diseases. The aim of this chapter is to examine biomarkers relevant to cardiovascular diseases in order to identify targets where pharmacological treatment can act. In this chapter, we will examine the main markers of insulin resistance, inflammation, endothelial damage, and metabolism linked to cardiovascular diseases.