Empirical tests of some predictions from coalescent theory with applications to intraspecific phylogeny reconstruction.
Empirical tests of some predictions from coalescent theory with applications to intraspecific phylogeny reconstruction.
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发表时间：
1993-07
期刊：
影响因子：
3.3
通讯作者：
K. Crandall;Alan R. Templeton
中科院分区：
文献类型：
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作者：
K. Crandall;Alan R. Templeton
收集了果蝇种内限制性位点多态性的经验数据集，以检验来自聚结理论的假设。测试了三个主要观点：(1)样本中的单倍型频率包含了给定单倍型在一个梯形图中的拓扑位置信息；(2)单倍型的频率与该梯形图中其他单倍型的突变连接数量有关；(3)地理位置可以用来推断单倍型在一个梯形图中的拓扑位置。然后，这些关系可以通过两种方式用于更好地估计种内系统发育：(1)确定系统发育的根源；(2)解决进化图中的歧义。这一信息将允许人们减少可选择系统发生的数量，并将重建种内系统发生所涉及的不确定性纳入到严重依赖于树的拓扑结构的后续分析中。
Empirical data sets of intraspecific restriction site polymorphism in Drosophila have been gathered in order to test hypotheses derived from coalescent theory. Three main ideas are tested: (1) haplotype frequency in the sample contains information on the topological position of a given haplotype in a cladogram, (2) the frequency of a haplotype is related to the number of mutational connections to other haplotypes in the cladogram and (3) geographic location can be used to infer topological positioning of haplotypes in a cladogram. These relationships can then be used to better estimate intraspecific phylogenies in two ways: (1) rooting the phylogeny and (2) resolving ambiguities in a cladogram. This information will allow one to reduce the number of alternative phylogenies and incorporate the uncertainties involved in reconstructing intraspecific phylogenies into subsequent analyses that depend heavily on the topology of the tree.