CELL CONFIGURATIONS IN THE OLFACTORY TUBERCLE OF THE RAT
CELL CONFIGURATIONS IN THE OLFACTORY TUBERCLE OF THE RAT
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DOI：
10.1002/cne.902280409
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发表时间：
1984-01-01
影响因子：
2.5
通讯作者：
HEIMER, L
中科院分区：
文献类型：
--
作者：
MILLHOUSE, OE;HEIMER, L
用快速高尔基体法对大鼠嗅结节进行了研究。几种不同的细胞类型主要根据它们的体细胞的大小和树突的结构被识别出来。结节中最常见的神经元类型是中等大小的密集棘细胞。这些神经元的体细胞主要分布在致密的细胞层和多形层。它们还形成了直接将嗅结节与伏隔核和尾壳核联系起来的细胞桥。它们的树枝状树形状多样，有些是球形的，有些是两极的，还有一些是不对称的。轴突向背侧投射，深入到多形层。在途中，他们送出了无数的经络。这种细胞类型的一个大版本是新月形细胞。其他中等大小的神经元在致密细胞和多形层中也有胞体。它们包括梭形细胞，因为它们的细胞体的形状而得名，以及中等大小的缺乏脊椎的神经元。这两种类型的细胞都没有像中等大小的密集棘细胞那样高度分枝的树突树。小细胞有3种类型，它们的体细胞主要分布在致密的细胞层和分子层。矮小细胞靠近软膜表面，尽管它们的体细胞包含在致密的细胞层中，并且它们的轴突类似于中等大小的密集棘细胞。放射状细胞有大量的、相对较短的、无刺的树突，树突从圆形的体细胞向各个方向延伸。小的富含脊椎的细胞看起来就像中等大小的密集棘突神经元的微型版本。它们通常局限于分子层。大的无脊椎神经元，其胞体位于致密的细胞层和多形层，似乎是一个异质细胞群，因为它们的树突结构和树突树的形状和范围有细微的变化。大的、中等刺突的神经元比其他大的细胞少见；它们的体细胞在所有3层都有。卡列哈岛的颗粒细胞组成了最均匀的细胞群。它们只有几个树枝状，而且很薄。除中等大小的密集棘细胞和矮小细胞外，不同类型细胞的轴突分布不是很均匀。将结节中的不同细胞类型与伏隔核、尾壳核和苍白球中的细胞进行比较。结节中的某些细胞与基底节中的某些细胞之间存在着显著的结构相似性，以及这些结构之间的直接结构连续性，这表明嗅结节至少部分地代表了尾壳核和苍白球的腹侧延伸。
The rat olfactory tubercle was studied with the rapid Golgi method. Several distinct cell types were identified mainly on the basis of the size of their somata and the structure of their dendrites. The commonest neuron type in the tubercle is the medium-sized densely spined cell. The somata of these neurons occur chiefly in the dense cell and multiform layers. They also form the cell bridges that directly link the olfactory tubercle with the nucleus accumbens and caudate-putamen. Their dendritic trees exhibit a variety of shapes; some of them are spherical, some are bipolar, and others are asymmetrical. The axons project dorsally, deep into the multiform layer. En route they give off numerous collaterals. A large version of this cell type is the crescent cell. Other medium-sized neurons also have somata in the dense cell and multiform layers. They include the spindle cells, so named because of the shape of their cell bodies, and the medium-sized spine-poor neurons. Neither of these cell types has dendritic trees that are as highly branched as those of the medium-sized densely spined cells. There are 3 types of small cells; their somata occur primarily in the dense cell and molecular layers. The dwarf cells are near the pial surface, although their somata are included in the dense cell layer, and they have axons that resemble those of medium-sized densely spined cells. The radiate cells have numerous, relatively short, spine-free dendrites that extend out from the rounded somata in all directions. The small spine-rich cells look like miniature versions of the medium-sized densely spined neurons. They are frequently confined to the molecular layer. Large spine-poor neurons, with their cell bodies located in the dense cell and multiform layers, seem to be a heterogeneous cell group since there are subtle variations in the structure of their dendrites and the shape and extent of their dendritic trees. The large, moderately spined neurons are less common than the other large cells; their somata are found in all 3 layers. The granule cells of the islands of Calleja make up the most homogeneous cell group. They have only a few dendrites, and are thin. Except for the medium-sized densely spined and dwarf cells, the axons of the different cell types were not very well impregnated. The different cell types in the tubercle are compared to cells in the nucleus accumbens, caudate-putamen, and globus pallidus. The remarkable structural similarities that exist between certain cells in the tubercle and some in the basal ganglia and the direct structural continuity that occurs between these structures indicate that the olfactory tubercle, at least in part, represents a ventral extension of the caudate-putamen and globus pallidus.