LIVER-TRANSPLANTATION WITH USE OF CYCLOSPORIN-A AND PREDNISONE
LIVER-TRANSPLANTATION WITH USE OF CYCLOSPORIN-A AND PREDNISONE
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DOI：
10.1056/nejm198107303050507
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发表时间：
1981-01-01
影响因子：
158.5
通讯作者：
SCHROTER, GPJ
中科院分区：
文献类型：
--
作者：
STARZL, TE;KLINTMALM, GBG;SCHROTER, GPJ
方法14例患者(年龄8~41岁)参加先导试验。1980年3月10日至9月28日期间曾尝试肝脏置换手术。两名原计划接受环孢素A联合泼尼松治疗的患者在手术中死亡。其中一人因门静脉撕裂失血过多而死亡，另一人接受了太大的同种异体移植，无法关闭腹部。因此，只有12名患者接受了免疫抑制治疗。
MethodsFourteen patients (age range, eight to 41 years) were accepted for the pilot trial. Liver replacement was attempted between March 10 and September 28, 1980. Two patients who were scheduled to be treated with cyclosporin A plus prednisone died during operation. One bled to death from a laceration of the portal vein, and the other received a homograft too large to permit the abdomen to be closed. Thus only 12 patients were treated with immunosuppression.