Effect of balloon pre-dilation on performance of self-expandable nitinol stent in femoropopliteal artery.

Effect of balloon pre-dilation on performance of self-expandable nitinol stent in femoropopliteal artery.
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DOI:
10.1007/s10237-022-01641-x
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发表时间:
2023-02
影响因子:
3.5
通讯作者:
Silberschmidt, Vadim V.
Silberschmidt, Vadim V.
中科院分区:
工程技术2区
文献类型:
--
作者:
He, Ran;Zhao, Liguo;Silberschmidt, Vadim V.

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对于严重堵塞或钙化斑块的情况,通常在股腘动脉植入镍钛合金支架之前进行球囊预扩张。然而,尚未研究其对病变股腘动脉中镍钛合金支架性能的影响。本研究通过对支架展开的整个过程进行建模,比较了有预扩张和无预扩张的支架植入术的结局。植入支架的疲劳变形也在舒张期-收缩期血压、重复弯曲、扭转、轴向压缩及其组合下建模。在预扩张的支架植入后,支架中的应力水平降低,但导致介质层(即动脉壁的中间层)的损伤增加。通常,预扩张会增加镍钛合金支架疲劳失效的风险。此外,根据支架植入引起的中膜层组织损伤预测支架内再狭窄的发生,并且预扩张、支架展开或疲劳载荷不会对中膜层引起严重的机械刺激。
Balloon pre-dilation is usually performed before implantation of a nitinol stent in a femoropopliteal artery in a case of severe blockage or calcified plaque. However, its effect on performance of the nitinol stent in a diseased femoropopliteal artery has not been studied yet. This study compares the outcomes of stenting with pre-dilation and without it by modelling the entire processes of stent deployment. Fatigue deformation of the implanted stent is also modelled under diastolic–systolic blood pressure, repetitive bending, torsion, axial compression and their combination. Reduced level of stress in the stent occurs after stenting with pre-dilation, but causing the increased damage in the media layer, i.e. the middle layer of the arterial wall. Generally, pre-dilation increases the risk of nitinol stent’s fatigue failure. Additionally, the development of in-stent restenosis is predicted based on the stenting-induced tissue damage in the media layer, and no severe mechanical irritation is induced to the media layer by pre-dilation, stent deployment or fatigue loading.
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