FRUCTOSE 2,6-BISPHOSPHATE, THE PROBABLE STRUCTURE OF THE GLUCOSE-SENSITIVE AND GLUCAGON-SENSITIVE STIMULATOR OF PHOSPHOFRUCTOKINASE

FRUCTOSE 2,6-BISPHOSPHATE, THE PROBABLE STRUCTURE OF THE GLUCOSE-SENSITIVE AND GLUCAGON-SENSITIVE STIMULATOR OF PHOSPHOFRUCTOKINASE
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DOI:
10.1042/bj1920897
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发表时间:
1980-01-01
影响因子:
4.1
通讯作者:
HERS, HG
HERS, HG
中科院分区:
生物学3区
文献类型:
--
作者:
VANSCHAFTINGEN, E;HUE, L;HERS, HG

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磷酸果糖激酶的低分子量刺激剂[货车Schaftingen,Hue & Hers(1980)Biochem.J.192,887-895]已从大鼠肝脏中纯化。在20 ℃下与0.01 M-HCl孵育10 min后,其被完全破坏,并形成果糖6-磷酸和与酸不稳定有机磷酸盐量相当的还原力。因此,它被初步鉴定为果糖2,6-二磷酸。
The low-molecular-weight stimulator of phosphofructokinase [Van Schaftingen, Hue & Hers (1980) Biochem. J. 192, 887-895] has been purified from rat liver. It was completely destroyed upon incubation with 0.01 M-HCl for 10 min at 20 degrees C and fructose 6-phosphate and a reducing power equivalent in amount to the acid-labile organic phosphate were formed. It was therefore tentatively identified as fructose 2,6-bisphosphate.