Comparative studies on the hypolipidemic and growth suppressive effects of oolong, black, pu-erh, and green tea leaves in rats
Comparative studies on the hypolipidemic and growth suppressive effects of oolong, black, pu-erh, and green tea leaves in rats
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DOI：
10.1021/jf049375k
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发表时间：
2005-01-26
影响因子：
6.1
通讯作者：
Lin, JK
中科院分区：
文献类型：
--
作者：
Kuo, KL;Weng, MS;Lin, JK
四种主要的商业茶，乌龙茶，红茶，普洱茶和绿色茶，都是在东南亚生产的。在这项研究中，我们评估了这四种不同的茶叶口服喂养雄性SD大鼠30周的生长抑制和降血脂作用。结果表明，对各茶组体重的抑制作用大小为：乌龙茶>普洱茶>红茶>绿色茶。普洱茶和乌龙茶降低甘油三酯的效果优于绿色茶和红茶，但普洱茶和绿色茶降低胆固醇的效果优于乌龙茶和红茶。在脂蛋白方面，4%普洱茶能提高HDL-C水平，降低LDL-C水平，而其它茶类则只是降低两者水平。与基础饲料喂养组相比，所有茶喂养组的抗氧化酶SOD活性均增加。最后，肝脏与附睾脂肪组织的相对重量比在喂食乌龙茶和普洱茶的组中较低。在这些发现的基础上，似乎完全发酵的普洱茶和红茶叶和部分发酵的乌龙茶叶比未发酵的绿色茶叶更有效地抑制生长和降血脂作用。
The four major commercial teas, oolong, black, pu-erh, and green teas, have been manufactured in southeast Asia. In this study, we evaluated the growth suppressive and hypolipidemic effect of these four different tea leaves by oral feeding to male Sprague-Dawley rats for 30 weeks. The results showed that the suppression of body weights of tea leaves-fed groups were in the order: oolong tea > pu-erh tea > black tea > green tea. Pu-erh tea and oolong tea could lower the levels of triglyceride more significantly than that of green tea and black tea, but pu-erh tea and green tea were more efficient than oolong tea and black tea in lowering the level of total cholesterol. In lipoprotein, 4% pu-erh tea could increase the level of HDL-C and decrease the level of LDL-C, but other teas simply decrease the levels of both. The activity of antioxidant enzyme SOD is increased in all tea-fed groups as compared to the basal diet-fed group. Finally, relative weight ratios of liver to epididylmal adipose tissue were lower in feeding oolong tea and pu-erh tea groups. On the basis of these findings, it seemed that the fully fermented pu-erh and black tea leaves and partially fermented oolong tea leaves were more effective on their growth suppressive and hypolipidemic effects as compared to the nonfermented green tea leaves.