Looking for the roots of cortical sensory computation in three-layered cortices.

Looking for the roots of cortical sensory computation in three-layered cortices.
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寻找三层皮层中皮质感觉计算的根。

DOI:
10.1016/j.conb.2014.09.006
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发表时间:
2015-04
影响因子:
5.7
通讯作者:
Laurent G
Laurent G
中科院分区:
医学2区
文献类型:
--
作者:
Fournier J;Müller CM;Laurent G

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尽管经过了世纪的努力,以及过去几十年来的技术进步,我们仍然远远没有了解哺乳动物的大脑皮层。同皮层有六层结构、模块化结构、规范电路、无数的细胞类型和计算复杂性,它仍然是一个具有挑战性的谜。在这篇综述中,我们认为,识别哺乳动物梨状皮质和爬行动物背侧皮质之间的结构和功能相似性,可以帮助揭示共同的组织和计算原则,并通过扩展,一些最原始的计算进行皮层网络。
Despite considerable effort over a century and the benefit of remarkable technical advances in the past few decades, we are still far from understanding mammalian cerebral cortex. With its six layers, modular architecture, canonical circuits, innumerable cell types, and computational complexity, isocortex remains a challenging mystery. In this review, we argue that identifying the structural and functional similarities between mammalian piriform cortex and reptilian dorsal cortex could help reveal common organizational and computational principles and by extension, some of the most primordial computations carried out in cortical networks.