RECOVERY FROM SHORT-TERM ADAPTATION IN SINGLE NEURONS IN THE COCHLEAR NUCLEUS
RECOVERY FROM SHORT-TERM ADAPTATION IN SINGLE NEURONS IN THE COCHLEAR NUCLEUS
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DOI：
10.1016/0378-5955(90)90203-2
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发表时间：
1990-09-01
期刊：
影响因子：
2.8
通讯作者：
SAUNDERS, SS
中科院分区：
文献类型：
--
作者：
BOETTCHER, FA;SALVI, RJ;SAUNDERS, SS
从短期适应恢复耳蜗核中的单个神经元使用前掩蔽刺激范例。在单位的特征频率（CF）的掩蔽音呈现之前和之后，测量对短持续时间，低电平探测音的反应。适应程度定义为在适应和不适应条件下发射探针的比率。掩蔽物的水平以及掩蔽物偏移和探测器开始（“DT”）之间的时间差是变化的。随着DT的增加，大多数Primarylike、Primarylike-notch和Chopper单元对探针的反应也增加。对于大多数这些单位，回收率在对数时间内近似呈线性。然而，大约有一半的暂停/建立和单位表现出非常不同的恢复模式，从没有适应非常非线性的恢复模式。结果表明，在恢复过程中发生的听神经和Primarylike，Primarylike-notch，和斩波器的单位之间的变化不大，但在恢复过程中发生的显着变化，暂停建立和单位。
Recovery from short-term adaptation was measured in single neurons in the cochlear nucleus using a forward masking stimulus paradigm. The response to a short-duration, low-level probe tone at a unit''s characteristic frequency (CF) was measured before and after presentation of a masker tone at the unit''s CF. The degree of adaptation was defined as the ratio of firing to the probe in the adapted and unadapted conditions. The level of the masker and time differences between the masker offset and probe onset (''DT'') were varied. As DT increased, the response to the probe increased in most Primarylike, Primarylike-notch, and Chopper units. Recovery was approximately linear in log time for most of these units. However, approximately half the Pauser/Buildup and On units showed very different recovery patterns, ranging from no adaptation to very non-linear recovery patterns. The results suggest that little alteration in the recovery process occurs between the auditory nerve and Primarylike, Primarylike-notch, and Chopper units, but that significant changes in the recovery process occur in Pauser-Buildup and On units.