Integrating Multiple Quantitative Proteomic Analyses Using MetaMSD.
Integrating Multiple Quantitative Proteomic Analyses Using MetaMSD.
复制标题
使用 MetaMSD 整合多种定量蛋白质组分析。
DOI:
10.1007/978-1-0716-1967-4_16
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发表时间:
2023
期刊:
影响因子:
--
通讯作者:
Kim,Sujung
中科院分区:
文献类型:
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作者:
Ryu,SoYoung;Yun,MiriamP;Kim,Sujung
MetaMSD is a proteomic software that integrates multiple quantitative mass spectrometry data analysis results using statistical summary combination approaches. By utilizing this software, scientists can combine results from their pilot and main studies to maximize their biomarker discovery while effectively controlling false discovery rates. It also works for combining proteomic datasets generated by different labeling techniques and/or different types of mass spectrometry instruments. With these advantages, MetaMSD enables biological researchers to explore various proteomic datasets in public repositories to discover new biomarkers and generate interesting hypotheses for future studies. In this protocol, we provide a step-by-step procedure on how to install and perform a meta-analysis for quantitative proteomics using MetaMSD.