Association between maternal weight gain and birth weight

Association between maternal weight gain and birth weight
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DOI:
10.1097/01.aog.0000266556.69952.de
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发表时间:
2007-06-01
影响因子:
7.2
通讯作者:
Ottesen, Bent
Ottesen, Bent
中科院分区:
医学2区
文献类型:
--
作者:
Rode, Line;Hegaard, Hanne K.;Ottesen, Bent

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目的:探讨母亲体重增加与出生体重小于3,000 g和大于或等于4,000 g的体重不足之间的关系(体重指数[BMI]小于19.8 kg /m(2)),体重正常(BMI 19.8-26.0 kg/ m(2)),超重(BMI 26.1-29.0 kg/m2),肥胖(BMI大于29.0 kg/m2)的女性,重点是使用美国医学研究所(IOM)在丹麦的建议。我们分析了2,248例单胎足月妊娠妇女的数据。体重增加和风险之间的关系,出生体重小于3,000 g和大于或等于4,000 g的四个BMI组进行了检查,并使用IOM的建议进行了测试,通过logistic回归analysis.Results:我们发现了一个负相关的母亲体重增加和婴儿的出生体重小于3,000 g的比例。出生体重大于或等于4,000 g的体重增加,体重不足和正常体重的妇女体重增加,但这种关联在超重和肥胖妇女中不太明显。体重不足的妇女似乎受益于增加比IOM推荐的更多的体重,因为出生体重小于3,000 g的比值比(OR)为0.3(95%置信区间[CI] 0.1-0.9),出生体重大于或等于4,000 g的OR为1.7(95% CI 0.8-3.6)。体重正常的妇女出生体重低于3,000克的风险增加(OR 2.4,95%CI 1.5-3.7),出生体重≥ 4,000 1的OR为1.9(95% CI 1.5-2.5)结论:IOM的建议可为丹麦向孕妇提出的建议提供依据,尽管可能必须提高体重不足妇女的建议上限。
Objective: To investigate the association between maternal weight gain and birth weight less than 3,000 g and greater than or equal to 4,000 g in underweight (body mass index [BMI] less than 19.8 kg /m(2)), normal weight (BMI 19.8-26.0 kg/ m(2)), overweight (BMI 26.1-29.0 kg/ m(2)), and obese (BMI greater than 29.0 kg/m(2)) women, with emphasis on the use of the American Institute of Medicine (IOM) recommendations in Denmark.Methods: We analyzed data from 2,248 women with singleton, term pregnancies. The relationship between weight gain and risk of birth weight less than 3,000 g and greater than or equal to 4,000 g was examined in the four BMI groups, and use of IOM recommendations was tested by logistic regression analyses.Results: We found an inverse relationship between maternal weight gain and the proportion of infants with a birth weight less than 3,000 g. Birth weight greater than or equal to 4,000 g increased with an increasing weight gain in underweight and normal-weight women, but the association was less apparent in overweight and obese women. Underweight women seemed to benefit from gaining more weight than recommended by the IOM, because the odds ratio (OR) of birth weight less than 3,000 g was 0.3 (95% confidence interval [CI] 0.1-0.9) and the OR was 1.7 for birthweight greater than or equal to 4,000 g (95% CI 0.8-3.6). The normal-weight women had an increased risk of birth weight less than 3,000 g (OR 2.4, 95% CI 1.5-3.7) if weight gain was below the recommended range, and the OR of birth weight greater than or equal to 4,000 1, was 1.9 (95% CI 1.5-2.5)Conclusion: The IOM recommendations may provide a basis for Danish recommendations to pregnant women, although the upper recommended limit for underweight women may have to be increased.