Association between urinary sodium-to-potassium ratio and home blood pressure and ambulatory blood pressure: the Ohasama study
Association between urinary sodium-to-potassium ratio and home blood pressure and ambulatory blood pressure: the Ohasama study
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尿钠钾比与家庭血压和动态血压之间的关联：Ohasama 研究
DOI：
10.1097/hjh.0000000000003087
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发表时间：
2022
影响因子：
4.9
通讯作者：
Ohkubo
中科院分区：
文献类型：
--
作者：
Muroya Tomoko;Satoh Michihiro;Murakami Takahisa;Nakayama Shingo;Asayama Kei;Hirose Takuo;Tatsumi Yukako;Inoue Ryusuke;Tsubota-Utsugi Megumi;Hara Azusa;Kogure Mana;Nakaya Naoki;Nomura Kyoko;Kikuya Masahiro;Metoki Hirohito;Imai Yutaka;Hozawa Atsushi;Ohkubo
目的：在同一队列中，尚无研究证明尿钠钾（Na/K）比值与所有门诊外血压（BP）[在家早晨和晚上BP（在家自我测量），以及24小时、白天和夜间动态BP]之间的相关性。我们的目的是评估，哪种类型的办公室外的BP更强烈地与尿Na/K比在一般population.Methods：这项横断面研究是在日本Ohasama的一般人群进行的。测量了家庭和动态血压水平，并从875名参与者（男性，25.5%;平均年龄，60.1岁）获得24小时尿样。结果：尿Na/K比值的中位数（四分位距）为4.19（3.36-5.26）。在尿Na/K比值的四分位数中，观察到家庭早晨、家庭晚上、24小时和白天SBP的显著正趋势（趋势P< 0.041;尿Na/K比值Q1和Q4之间的校正平均值：121.0-125.5 mmHg（家庭早晨），120.1-123.8 mmHg（家庭晚上），121.6-123.4 mmHg（24小时），127.5-129.5 mmHg（白天））。尿Na/K比值与办公室或夜间收缩压和夜间血压下降无显著相关性（趋势P> 0.13）。结论：尿Na/K比值与家庭血压的相关性可能比与24 h和白天血压的相关性更强，但与夜间血压的相关性不明显。
Objective:No studies have demonstrated the association between urinary sodium-to-potassium (Na/K) ratio and all out-of-office blood pressure (BP)[home morning and evening BP (self-measured at home), and 24-h, daytime, and night-time ambulatory BP] in the same cohort. We aimed to assess, which type of out-of-office BP is more strongly associated with urinary Na/K ratio in the general population.Methods:This cross-sectional study was conducted in the general population of Ohasama, Japan. Home and ambulatory BP levels were measured, and 24-h urine samples were obtained from 875 participants (men, 25.5%; mean age, 60.1 years). The urinary Na/K ratio in the 24-h urine samples was calculated.Results:The median (interquartile range) urinary Na/K ratio was 4.19 (3.36–5.26). Significant positive trends of home morning, home evening, 24-h, and daytime SBP were observed across quartiles of urinary Na/K ratio (trend P< 0.041; adjusted mean values between Q1 and Q4 of urinary Na/K ratio: 121.0–125.5 mmHg for home morning, 120.1–123.8 mmhg for home evening, 121.6–123.4 mmHg for 24-h, 127.5–129.5 mmHg for daytime). Urinary Na/K ratio was not significantly associated with office or night-time SBP and nocturnal BP fall (trend P> 0.13). In the model with both home morning or evening SBP and daytime SBP, only home SBP was significantly associated with urinary Na/K ratio (P< 0.048 for home SBP).Conclusion:These findings suggest that urinary Na/K ratio might be more strongly associated with home BP than with 24-h and daytime BP but was not associated with night-time BP.
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影响因子：
--
作者：
Cook, Nancy R.;Obarzanek, Eva;Cutler, Jeffrey A.;Buring, Julie E.;Rexrode, Kathryn M.;Kumanyika, Shiriki K.;Appel, Lawrence J.;Whelton, Paul K.
通讯作者：
Whelton, Paul K.
家庭血压测量与中风发病率的预测价值：日本大笠间的一项基于人群的试点研究。
影响因子：
5.4
作者：
M. Sakuma;Y. Imai;I. Tsuji;K. Nagai;T. Ohkubo;N. Watanabe;H. Sakuma;H. Satoh;S. Hisamichi
通讯作者：
S. Hisamichi
影响因子：
12.3
作者：
Hozawa, Atsushi;Kuriyama, Shinichi;Tsuji, Ichiro
通讯作者：
Tsuji, Ichiro
影响因子：
8.3
作者：
Kim, Mi Kyung;Kwon, Minji;Jo, Sang-Ho
通讯作者：
Jo, Sang-Ho
学龄前儿童尿钠和钾排泄水平：个体、每日和季节差异
DOI：
10.1111/jch.12966
发表时间：
2017
期刊：
The Journal of Clinical Hypertension
影响因子：
--
作者：
K. Yasutake;Mikako Nagafuchi;Ryoji Izu;Tomomi Kajiyama;K. Imai;Yusuke Murata;K. Ohe;M. Enjoji;T. Tsuchihashi
通讯作者：
T. Tsuchihashi