Study supports the introduction of early medical abortion in Turkey

Study supports the introduction of early medical abortion in Turkey
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DOI:
10.1016/s0968-8080(05)26207-9
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发表时间:
2005-11-01
影响因子:
--
通讯作者:
Akin, L
Akin, L
中科院分区:
医学3区
文献类型:
--
作者:
Akin, A;Kocoglu, GO;Akin, L

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在土耳其,公共卫生服务部门提供的人工流产服务的需求尚未得到满足,特别是在农村和城乡结合部地区。这项临床研究的目的是表明土耳其可以安全地引入早期药物流产,以改善妇女获得服务的机会。在这项研究中,年龄在 18-49 岁、妊娠 56 天以内的女性可以选择药物流产,即先服用 200 毫克米非司酮,然后口服 400 微克米索前列醇,再进行局部麻醉 MVA。 209 人选择药物流产,149 人选择手术流产。另外还收集了 112 名妇女的数据,以获得类似数量的手术流产病例。记录截至 14 天随访期间女性对所选方法的偏好和满意度、副作用和并发症。 75% 选择药物流产的女性选择在家使用米索前列醇。药物流产的疼痛平均持续 3.6 +/- 3.0 天,手术流产的疼痛平均持续 3.7 +/- 2.9 天。 90% 接受过药物流产的女性表示,与 70% 接受过手术流产的女性相比,她们更愿意再次进行流产。药物流产组中有 1.4% 的人继续妊娠,而手术组则没有。提供者的培训和对药物流产的熟悉至关重要。高不全流产率表明应重新考虑米索前列醇的剂量和方案。研究结果支持在土耳其引入早期药物流产 (c) 2005 年生殖健康问题。版权所有。
In Turkey, there is an unmet need for induced abortion services provided by the public health services, especially in rural and semi-urban areas. The objective of this clinical study was to show that early medical abortion could be introduced safely in Turkey to improve women's access to services. In the study, women aged 18-49 up to 56 days of pregnancy were offered a choice between medical abortion with 200mg mifepristone followed by 400mcg oral misoprostol and MVA with local anaesthesia. 209 chose medical and 149 surgical abortion. Data from an additional 112 women were collected to obtain a similar number of surgical abortion cases. Womens preference for and satisfaction with the chosen method, side effects and complications up to the 14-day follow-up visit were recorded. 75% of women who chose medical abortion opted for home use of misoprostol. Pain with medical abortion on average lasted 3.6 +/- 3.0 days and with surgical abortion 3.7 +/- 2.9 days. 90% of women who had medical abortion said they would prefer it again compared to 70% of those having surgical abortion. There were 1.4% ongoing pregnancies in the medical abortion group and none in the surgical group. Provider training and familiarity with medical abortion are crucial. The high incomplete abortion rate indicates that the dose and regimen of misoprostol should be reconsidered. The findings support the introduction of early medical abortion in Turkey (c) 2005 Reproductive Health Matters. All rights reserved.