Pediatric arterial ischemic stroke: Epidemiology, risk factors, and management
Pediatric arterial ischemic stroke: Epidemiology, risk factors, and management
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DOI：
10.1016/j.bcmd.2017.03.003
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发表时间：
2017-09-01
影响因子：
2.3
通讯作者：
Bernard, Timothy
中科院分区：
文献类型：
--
作者：
Felling, Ryan J.;Sun, Lisa R.;Bernard, Timothy
小儿动脉缺血性卒中（AIS）是新生儿和儿童神经系统发病的一种罕见但重要的原因，其后果包括轻偏瘫、智力残疾和癫痫。儿童AIS的病因与成人卒中的典型病因不同。熟悉儿童AIS的危险因素将有助于有效诊断，不幸的是，这经常被延迟。在这里，我们审查的流行病学和危险因素的AIS在新生儿和儿童。我们还概述了在儿科AIS的评估和管理中基于共识的实践。最后，我们讨论了在这一人群中观察到的结果。虽然近几十年来已经了解了很多，但儿科AIS仍存在许多不确定性。致力于儿科卒中的专业中心和研究人员的持续发展将继续回答这些问题，并提高我们有效护理这些患者的能力。(C)2017爱思唯尔公司All rights reserved.
Pediatric arterial ischemic stroke (AIS) is an uncommon but important cause of neurologic morbidity in neonates and children, with consequences including hemiparesis, intellectual disabilities, and epilepsy. The causes of pediatric AIS are unique to those typically associated with stroke in adults. Familiarity with the risk factors for AIS in children will help with efficient diagnosis, which is unfortunately frequently delayed. Here we review the epidemiology and risk factors for AIS in neonates and children. We also outline consensus-based practices in the evaluation and management of pediatric AIS. Finally we discuss the outcomes observed in this population. While much has been learned in recent decades, many uncertainties sill persist in regard to pediatric AIS. The ongoing development of specialized centers and investigators dedicated to pediatric stroke will continue to answer such questions and improve our ability to effectively care for these patients. (C) 2017 Elsevier Inc. All rights reserved.