Effects of surface roughness and maximum load on the mechanical properties of cancellous bone measured by nanoindentation
Effects of surface roughness and maximum load on the mechanical properties of cancellous bone measured by nanoindentation
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DOI：
10.1002/jbm.a.30633
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发表时间：
2006-05-01
影响因子：
4.9
通讯作者：
van der Meulen, MCH
中科院分区：
文献类型：
--
作者：
Donnelly, E;Baker, SP;van der Meulen, MCH
以脱水兔松质骨为材料，考察了两个关键实验参数对板层和板间组织纳米力学性能的影响。开发了一种无水样品制备方案，以保持表面完整性并产生类似于10 nm(5×5-mum(2)面积)的均方根表面粗糙度。在最大载荷范围为250~3000mN的两个不同表面粗糙度的样品中，考察了表面粗糙度和最大纳米压痕载荷对测量的力学性能的影响。当压痕深度与表面粗糙度之比降至接近3：1时，材料性能的变异性显著增加。在低载荷下，板层骨的压痕模数比板层间骨的大20%，而在高载荷下，两层骨的测量性能都收敛到一个中间值。光滑表面较浅的压痕显示板层骨和板层间骨的性质有显著差异，支持板层骨比板层间骨矿化程度更高的微观结构观察。(C)2005年威利期刊公司。
The effects of two key experimental parameters on the measured nanomechanical properties of lamellar and interlametlar tissue were examined in dehydrated rabbit cancellous bone. An anhydrous sample preparation protocol was developed to maintain surface integrity and produce RMS surface roughnesses similar to 10 nm (5 X 5-mu m(2) area). The effects of surface roughness and maximum nanoindentation load on the measured mechanical properties were examined in two samples of differing surface roughness using maximum loads ranging from 250 to 3000 mu N. As the ratio of indentation depth to surface roughness decreased below similar to 3:1, the variability in material properties increased substantially. At low loads, the indentation modulus of the lamellar bone was similar to 20% greater than that of the interlamellar bone, while at high loads the measured properties of both layers converged to an intermediate value. Relatively shallow indentations made on smooth surfaces revealed significant differences in the properties of lamellar and interlamellar bone that support microstructural observations that lamellar bone is more mineralized than interlamellar bone. (c) 2005 Wiley Periodicals, Inc.