Risk factors for vascular dementia and Alzheimer disease
Risk factors for vascular dementia and Alzheimer disease
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DOI：
10.1161/01.str.0000143318.70292.47
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发表时间：
2004-11-01
期刊：
影响因子：
8.3
通讯作者：
Gorelick, PB
中科院分区：
文献类型：
--
作者：
Gorelick, PB
阿尔茨海默病和血管性认知障碍是老年人认知功能下降的重要原因。现在已经证明，血管危险因素对大脑有可测量的负面影响，并与认知障碍有关。我们综述了可能导致阿尔茨海默病认知功能下降的血管因素和血管性认知障碍，以及随着年龄的增长可能预防认知障碍的相应干预措施。
Alzheimer disease and vascular cognitive impairment are important causes of cognitive decline in the elderly. It has now been shown that vascular risk factors have measurable negative effects on the brain and are associated with cognitive impairment. We review vascular factors that might be responsible to cognitive decline in Alzheimer disease and vascular cognitive impairment and the corresponding intervenvations that might prevent cognitive impairment as we age.