A Presynaptic Liquid Phase Unlocks the Vesicle Cluster.
A Presynaptic Liquid Phase Unlocks the Vesicle Cluster.
复制标题
突触前液相解锁囊泡簇。
DOI:
10.1016/j.tins.2018.07.009
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发表时间:
2018
影响因子:
15.9
通讯作者:
Kaeser,PascalS
中科院分区:
文献类型:
--
作者:
Wang,ShanShanH;Kaeser,PascalS
How are synaptic vesicles tied together in a nerve terminal? A recent study by Milovanovic and colleagues offers a new mechanism for this old and important problem: synapsin proteins establish a liquid phase that clusters vesicles. Liquid–liquid phase separation provides a fluid-like state that accommodates the dynamic demands of presynaptic vesicle traffic.