Transcranial direct current stimulation during treadmill training in children with cerebral palsy: A randomized controlled double-blind clinical trial
Transcranial direct current stimulation during treadmill training in children with cerebral palsy: A randomized controlled double-blind clinical trial
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DOI：
10.1016/j.ridd.2014.07.030
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发表时间：
2014-11-01
影响因子：
3.1
通讯作者：
Oliveira, Claudia Santos
中科院分区：
文献类型：
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作者：
Collange Grecco, Luanda Andre;Carvalho Duarte, Natalia de Almeida;Oliveira, Claudia Santos
步态障碍是脑性瘫痪（CP）儿童重要的功能限制。跑步机训练已经取得了令人鼓舞的结果，改善了这一人群的步态模式。此外，经颅直流电刺激（tDCS）被认为是加强在运动康复过程中取得的结果。本研究的目的是确定踏车训练期间给予tDCS对痉挛性轻瘫CP儿童步态模式的影响。进行了一项双盲随机对照试验，涉及24名CP儿童，在10次20分钟的跑步机训练期间，他们被分配到实验组（优势半球初级运动皮层上的主动阳极tDCS [1 mA]）或对照组（安慰剂tDCS）。实验组表现出改善的时间功能的流动性，步态变量（时空和运动学变量）。结果在干预结束后一个月保持不变。与对照组相比，皮质脊髓兴奋性有显着变化。在本研究中，在踏车训练期间给予tDCS增强了痉挛型轻瘫CP儿童运动训练的效果。(C)2014爱思唯尔有限公司版权所有。
Impaired gait constitutes an important functional limitation in children with cerebral palsy (CP). Treadmill training has achieved encouraging results regarding improvements in the gait pattern of this population. Moreover, transcranial direct current stimulation (tDCS) is believed to potentiate the results achieved during the motor rehabilitation process. The aim of the present study was to determine the effect of the administration of tDCS during treadmill training on the gait pattern of children with spastic diparetic CP. A double-blind randomized controlled trial was carried out involving 24 children with CP allocated to either an experimental group (active anodal tDCS [1 mA] over the primary motor cortex of the dominant hemisphere) or control group (placebo tDCS) during ten 20-min sessions of treadmill training. The experimental group exhibited improvements in temporal functional mobility, gait variables (spatiotemporal and kinematics variables). The results were maintained one month after the end of the intervention. There was a significant change in corticospinal excitability as compared to control group. In the present study, the administration of tDCS during treadmill training potentiated the effects of motor training in children with spastic diparetic CP. (C) 2014 Elsevier Ltd. All rights reserved.