Emotional arousal and activation of the visual cortex: An fMRI analysis
Emotional arousal and activation of the visual cortex: An fMRI analysis
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DOI：
10.1111/1469-8986.3520199
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发表时间：
1998-03-01
期刊：
影响因子：
3.7
通讯作者：
Nangia, V
中科院分区：
文献类型：
--
作者：
Lang, PJ;Bradley, MM;Nangia, V
当参与者观看一系列令人愉快、中性或不愉快的图片时，使用功能性磁共振成像技术评估视觉皮层的功能活动。在8个12秒的图片呈现期（开）和12秒的图片间隔（关）期间，在枕叶皮质的四个不同位置采集冠状图像。在处理所有图片内容的过程中，与图片间间隔相比，右侧半球的功能激活程度大于左侧半球，枕叶区域的功能激活程度大于枕顶区域。更重要的是，当处理情绪（愉快或不愉快）图片时，所有采样的大脑区域的功能活动都比处理中性刺激时要大得多。在实验2中，排除了这些差异是差异性眼球运动的伪影的假设。情绪图片和中性图片都能产生以距状沟（17区）为中心的活动，而只有情绪图片在双侧枕回、右侧梭状回、右侧顶下小叶和顶上级小叶也能产生相当大的集群。
Functional activity in the visual cortex was assessed using functional magnetic resonance imaging technology while participants viewed a series of pleasant, neutral, or unpleasant pictures. Coronal images at four different locations in the occipital cortex were acquired during each of eight 12-s picture presentation periods (on) and 12-s interpicture interval (off). The extent of functional activation was larger in the right than the left hemisphere and larger in the occipital than in the occipitoparietal regions during processing of all picture contents compared with the interpicture intervals. More importantly, functional activity was significantly greater in all sampled brain regions when processing emotional (pleasant or unpleasant) pictures than when processing neutral stimuli. In Experiment 2, a hypothesis that these differences were an artifact of differential eye movements was ruled out. Whereas both emotional and neutral pictures produced activity centered on the calcarine fissure (Area 17), only emotional pictures also produced sizable clusters bilaterally in the occipital gyrus, in the right fusiform gyrus, and in the right inferior and superior parietal lobules.