Childhood risk factors for high adult blood pressure: the Muscatine Study.
Childhood risk factors for high adult blood pressure: the Muscatine Study.
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DOI：
10.1542/peds.84.4.633
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发表时间：
1989-10
期刊：
影响因子：
8
通讯作者：
R. Lauer;W. Clarke
中科院分区：
文献类型：
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作者：
R. Lauer;W. Clarke
在成年人群中，血压升高与闭塞性动脉粥样硬化、中风和肾脏疾病的发生有关。儿童期血压水平的重要性，除非极度升高，否则与疾病结局无关。在这项研究中，高血压的风险在年轻的成年人生活的基础上的血压和其他因素在学龄期的观察进行评估。2445名受试者在7至18岁时首次观察，在20至30岁时再次观察。在儿童时期，每隔一年测量血压、身高和体重。在成年时，再次进行相同的测量，并进行健康问卷调查。根据数据，成人血压与儿童血压、体型以及从儿童到成人生活的体重变化相关。成人的肥胖与儿童的肥胖有关，那些成年后最肥胖的人从他们的童年时期开始，身高体重增加最多。这些观察结果表明，策略，以防止在青春期获得过多的ponderosity可能是有用的，在预防成人高血压。
In adult populations, elevated blood pressure is related to the development of occlusive atherosclerosis, stroke, and renal disease. The significance of blood pressure levels in childhood, unless extremely elevated, has not been related to disease outcomes. In this study, the risk of high blood pressure in young adult life is evaluated based on the observations of blood pressure and other factors made during the school-aged years. Subjects, 2445 in number, were first observed at ages 7 through 18 years and again between 20 and 30 years. During childhood, measurements of blood pressure, height, and weight were made in alternate years. At adult ages, the same measurements were again made and a health questionnaire was administered. According to the data, adult blood pressure is correlated with childhood blood pressure, body size, and change in ponderosity from childhood to adult life. Adult ponderosity is related to childhood ponderosity, and those who are most obese as adults show the greatest increase in weight for height from their childhood years. These observations suggest that strategies to prevent the acquisition of excess ponderosity during adolescence may be useful in preventing adult hypertension.