Cerebral: a Cytoscape plugin for layout of and interaction with biological networks using subcellular localization annotation
Cerebral: a Cytoscape plugin for layout of and interaction with biological networks using subcellular localization annotation
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DOI：
10.1093/bioinformatics/btm057
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发表时间：
2007-04-15
期刊：
影响因子：
5.8
通讯作者：
Munzner, Tamara
中科院分区：
文献类型：
--
作者：
Barsky, Aaron;Gardy, Jennifer L.;Munzner, Tamara
Cerebral（基于细胞区域的渲染和布局）是一款用于Cytoscape生物分子相互作用查看器的开源Java插件。给定一个相互作用网络和亚细胞定位注释，Cerebral会自动以传统通路图的样式生成该网络的视图，为探索生物通路或系统提供一个直观的界面。分子根据其亚细胞定位被分层。通路的潜在产物或结果可以显示在视图底部，例如根据任何分子属性数据（蛋白质功能）进行聚类。Cerebral对包含数千个节点的网络有很好的扩展性。
Cerebral (Cell Region-Based Rendering And Layout) is an open-source Java plugin for the Cytoscape biomolecular interaction viewer. Given an interaction network and subcellular localization annotation, Cerebral automatically generates a view of the network in the style of traditional pathway diagrams, providing an intuitive interface for the exploration of a biological pathway or system. The molecules are separated into layers according to their subcellular localization. Potential products or outcomes of the pathway can be shown at the bottom of the view, clustered according to any molecular attribute data-protein function-for example. Cerebral scales well to networks containing thousands of nodes.