Antibody Distribution Against Nonenteropathic E. Coli: Relation to Age, Sex, and Breast Feeding

Antibody Distribution Against Nonenteropathic E. Coli: Relation to Age, Sex, and Breast Feeding
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针对非肠病性大肠杆菌的抗体分布:与年龄、性别和母乳喂养的关系

DOI:
10.1001/archinte.1962.03620230122017
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发表时间:
1962
影响因子:
39
通讯作者:
C. Kunin
C. Kunin
中科院分区:
医学1区
文献类型:
--
作者:
C. Kunin

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Escherichia coli have been the subject of a vast number of studies since first characterized more than 75 years ago. They constitute the predominant flora of the colon of many animal species, including man, and have been shown to be of great importance in nutrition, in the metabolism of drugs, in certain diarrheal diseases, and in infections of the urinary tract. Conflicting evidence has been presented concerning the role their products play in the pathogenesis of irreversible shock. 1-3 Under ordinary conditions, these organisms do not appear to disturb the host; in certain circumstances, however, such as during the neonatal period, with hypogammaglobulinemia, localized obstruction, excessive irradiation, adrenal cortical steroid therapy, and neoplasia, they may become invasive and threaten life. 4 Certain strains which possess hemolytic activity, skin-necrotizing power, 5 and resistance to the bactericidal activity of serum 6,7 at times appear to be more invasive than others. In general,