Genomewide association studies and human disease.

Genomewide association studies and human disease.
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DOI:
10.1056/nejmra0808700
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发表时间:
2009-04-23
期刊:
The New England journal of medicine
影响因子:
--
通讯作者:
Singleton A
Singleton A
中科院分区:
其他
文献类型:
--
作者:
Hardy J;Singleton A

文献摘要

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全基因组关联研究已经发现了许多导致疾病易感性的遗传变异。本文描述了全基因组关联研究和可能解决其局限性的新方法。
Genomewide association studies have uncovered many genetic variants that confer susceptibility to disease. This article describes the genomewide association study and new approaches that may address some of its limitations.