Separate components of emotional go/no-go performance relate to autism versus attention symptoms in children with autism.
Separate components of emotional go/no-go performance relate to autism versus attention symptoms in children with autism.
复制标题
情绪进行/不进行表现的不同组成部分与自闭症儿童的自闭症和注意力症状有关。
DOI：
10.1037/a0033615
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发表时间：
2013
期刊：
影响因子：
2.4
通讯作者：
Wallace,GregoryL
中科院分区：
文献类型：
--
作者：
Yerys,BenjaminE;Kenworthy,Lauren;Jankowski,KathrynF;Strang,John;Wallace,GregoryL
目的探讨高功能自闭症儿童在情绪GO/NO-GO任务中是否会表现出反应抑制能力受损，以及注意缺陷多动障碍(ADHD)或自闭症症状的严重程度是否与成绩相关。方法44名儿童(21名符合自闭症标准；23名典型发展中的对照组[tDC])完成了一项情绪GO/NO-GO任务，其中情绪面部表情(愤怒、恐惧、高兴或悲伤)是GO刺激，中性面部表情是NO-GO刺激，反之亦然。此外，自闭症组中在情绪围棋试验中反应时间最快的儿童被评为具有最多症状的儿童(自闭症诊断观察表社交+沟通评分)，即使在考虑了与ADHD症状的关联之后也是如此。在所有试验中，自闭症组也比TDC组做出更多的冲动反应(即较低的d‘，更多的错误警报)。随着d‘的降低或错误警报的增加，ADHD的症状也会增加。多动/冲动症状与错误警报显著相关，而注意力不集中症状与错误警报无关。未通过错误警报与自闭症症状之间没有显著的关系；即使在分离出与自闭症症状的关联之后，ADHD症状与未通过错误警报之间的显著相关性仍然存在。结论本研究结果支持共病模型，该模型主张共享和独立的危险因素，因为ADHD和自闭症症状与情绪进行/不进行表现的独立方面相关。
ObjectiveThe present investigation examined whether higher functioning children with autism would demonstrate impaired response inhibition performance in an emotional go/no-go task, and whether severity of attention-deficit/hyperactivity disorder (ADHD) or autism symptoms correlated with performance.MethodForty-four children (21 meeting criteria for autism; 23 typically developing controls [TDCs]) completed an emotional go/no-go task in which an emotional facial expression (angry, fearful, happy, or sad) was the go stimulus and a neutral facial expression was the no-go stimulus, and vice versa.ResultsThe autism group was faster than the TDC group on all emotional go trials. Moreover, the children in the autism group who had the fastest reaction times on emotional go trials were rated as having the greatest number of symptoms (Autism Diagnostic Observation Schedule Social+ Communication score), even after accounting for the association with ADHD symptoms. The autism group also made more impulsive responses (ie, lower d′, more false alarms) than the TDC group on all trials. As d′ decreased or false alarms increased, so did ADHD symptoms. Hyperactivity/impulsivity symptoms were significantly correlated with false alarms, but inattention symptoms were not. There was not a significant relationship between no-go false alarms and autism symptoms; even after partialing out associations with autism symptoms, the significant correlation between ADHD symptoms and no-go false alarms remained.ConclusionThe present findings support a comorbidity model that argues for shared and independent risk factors, because ADHD and autism symptoms related to independent aspects of emotional go/no-go performance.