Adhesion of Candida albicans to mouse intestinal mucosa in vitro: development of the assay and test of inhibitors.

Adhesion of Candida albicans to mouse intestinal mucosa in vitro: development of the assay and test of inhibitors.
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白色念珠菌对小鼠肠粘膜的体外粘附:抑制剂测定和测试的发展。

DOI:
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发表时间:
1986
期刊:
Journal of Medical and Veterinary Mycology
影响因子:
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通讯作者:
Dwayne C. Savage
Dwayne C. Savage
中科院分区:
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文献类型:
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作者:
Esther Segal;Dwayne C. Savage

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本研究描述了一种用于估计粘附于小鼠肠粘膜的白色念珠菌数量的体外测定法。C.白色念珠菌粘附遗传上不同的小鼠品系,也没有在三个C.白色念珠菌菌株。甲壳素可溶性提取物,从C.白色假丝酵母菌或从商业获得的几丁质,分别抑制酵母菌对十二指肠组织的粘附48%和43%。
This study describes an in-vitro assay for estimating numbers of Candida albicans adherent to mouse intestinal mucosa. No significant differences were observed in the capacity of C. albicans to adhere to genetically distinct mouse strains nor in the binding ability of three C. albicans strains. Chitin soluble extracts, prepared from chitin isolated from C. albicans or from chitin obtained commercially, inhibited adhesion of the yeasts to duodenal tissue by 48% and 43%, respectively.