S-acylation by the DHHC protein family
S-acylation by the DHHC protein family
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DOI：
10.1042/bst0380522
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发表时间：
2010-04-01
影响因子：
3.9
通讯作者：
Chamberlain, Luke H.
中科院分区：
文献类型：
--
作者：
Greaves, Jennifer;Chamberlain, Luke H.
已鉴定出具有哺乳动物 S-酰基转移酶功能的 23 个 DHHC (Asp-His-His-Cys) 蛋白家族，这为蛋白质 S-酰化研究注入了新的活力。最近的研究不断揭示 S-酰化如何影响靶蛋白，并提供了如何实现 DHHC 底物特异性的一瞥。
A family of 23 DHHC (Asp-His-His-Cys) proteins that function as mammalian S-acyltransferases has been identified, reinvigorating the study of protein S-acylation. Recent studies have continued to reveal how S-acylation affects target proteins, and have provided glimpses of how DHHC-substrate specificity might be achieved.