Smartphone-Powered Electrochemical Dongle for Point-of-Care Monitoring of Blood β-Ketone
Smartphone-Powered Electrochemical Dongle for Point-of-Care Monitoring of Blood β-Ketone
复制标题
DOI：
10.1021/acs.analchem.7b02531
复制
发表时间：
2017-09-05
影响因子：
7.4
通讯作者：
Guo, Jinhong
中科院分区：
文献类型：
--
作者：
Guo, Jinhong
报道了一种智能手机供电的医用加密狗，它是一种微型电化学分析仪，与酶促β-羟基丁酸试纸相结合，可在护理点准确地表征外周全血血酮，能够为糖尿病酮症酸中毒(DK)和糖尿病酮症酸中毒(DKA)的评估和治疗提供关键指导。将医用加密狗的血酮测定结果与大型生化分析仪的临床结果进行了比较，分析结果具有良好的一致性。建议的医用智能手机供电的加密狗被证明是一个非常有前途的平台，作为一个微型电化学分析仪，用于医疗保健点监测关键生化参数，如血酮，以及移动健康管理的良好解决方案。
A smartphone-powered medical dongle as a miniaturized electrochemical analyzer associated with an enzymatic beta-hydroxybutyrate test strip for accurate characterization of blood ketone in peripheral whole blood at the point-of-care, which is capable of providing critical guidance for the evaluation and treatment of diabetic ketoacidosis (DK) and diabetic ketosis acid (DKA), is reported. The measured results of blood ketone by the medical dongle were compared with the clinical results from a bulky biochemical analyzer, and the analysis showed good agreement. The proposed medical smartphone-powered dongle was demonstrated to be a very promising platform as a miniaturized electrochemical analyzer for point-of-care monitoring of the critical biochemical parameters such as blood ketone and a good solution for mobile health management.