Maternal obesity and neonatal Apgar scores
Maternal obesity and neonatal Apgar scores
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DOI：
10.3109/14767050903168440
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发表时间：
2010-01-01
影响因子：
1.8
通讯作者：
Dammann, Olaf
中科院分区：
文献类型：
--
作者：
Chen, Minghua;McNiff, Ceara;Dammann, Olaf
Objective.确定母亲怀孕早期肥胖是否与新生儿5分钟Apgar评分低相关，同时调整混杂因素。数据来自缅因州出生记录数据库。分析仅限于58,089名白色妇女及其新生儿的信息。使用记录的孕中期早期母体体重指数（BMI）定义母体体重状态，并将其定义为正常体重（BMI < 25）、超重（BMI 25至< 30）、肥胖（BMI 30至< 40）和病态肥胖（BMI >= 40）。Logistic回归分析用于评估母亲体重状况与低Apgar评分的关系，同时调整混杂因素。与正常体重孕妇相比，肥胖孕妇（OR 1.4395% CI 1.1-1.7）和病态肥胖孕妇（OR 2.0395% CI 1.5-2.7）的新生儿Apgar评分低（4-6分）的风险增加。对于超重母亲的新生儿，这种关联没有达到显著性（OR 1.2，95% CI 0.99-1.4）。未发现母亲体重状况与极低Apgar评分（0-3）之间存在关联。母亲肥胖与出生时Apgar评分降低的风险显著增加相关。需要进一步的研究来阐明母亲肥胖、妊娠并发症和新生儿结局之间的关系。
Objective. To determine whether maternal obesity in early pregnancy is associated with low neonatal 5-min Apgar scores while adjusting for confounders.Methods. Data were obtained from Maine State Birth Records Database. Analyses were restricted to information on 58,089 white women and their newborns. Maternal weight status was defined using the recorded early second trimester maternal body mass index (BMI) and defined as normal weight (BMI < 25), overweight (BMI 25 to < 30), obese (BMI 30 to < 40), and morbidly obese (BMI >= 40). Logistic regression analysis was used to assess the association of maternal weight status with low Apgar score while adjusting for confounders.Results. Compared with newborns of normal weight women, the risk to receive low Apgar scores (4-6) is increased in newborns of obese (OR 1.43 95% CI 1.1-1.7) and morbidly obese mothers (OR 2.03 95% CI 1.5-2.7). The association did not achieve significance for newborns of overweight mothers (OR 1.2, 95% CI 0.99-1.4). No association was identified between maternal weight status and very low Apgar scores (0-3).Conclusions. Maternal obesity is associated with a significantly increased risk for decreased Apgar scores at birth. Further studies are needed to clarify the relationships among maternal obesity, complications of pregnancy, and neonatal outcome.