Functional outcome and health-related quality of life 10 years after moderate-to-severe traumatic brain injury
Functional outcome and health-related quality of life 10 years after moderate-to-severe traumatic brain injury
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DOI：
10.1111/j.1600-0404.2008.01116.x
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发表时间：
2009-07-01
影响因子：
3.5
通讯作者：
Roe, C.
中科院分区：
文献类型：
--
作者：
Andelic, N.;Hammergren, N.;Roe, C.
描述中重度创伤性脑损伤（TBI）后10年的功能结局和健康相关生活质量（HRQL）。对1995/1996年在挪威东部创伤转诊中心住院的62例中度至重度创伤性脑损伤的工作年龄幸存者进行回顾性、基于人群的研究。功能状态通过格拉斯哥结局扩展量表（GOS-E）进行测量。HRQL采用SF-36问卷评估。当前平均年龄为40.8岁。癫痫发生率为19%，抑郁症发生率为31%。大多数患者恢复良好（48%）或中度残疾（44%）。就业率为58%。与HRQL相比，功能和就业状况与初始损伤严重程度相关。与挪威普通人群相比，研究患者在所有SF-36维度上的得分明显较低。在10年的随访中，我们的研究人群仍处于最具生产力的年龄，应在长期随访和干预计划中考虑受影响的领域。
To describe the functional outcome and health-related quality of life (HRQL) 10 years after moderate-to-severe traumatic brain injury (TBI).A retrospective, population-based study of 62 survivors of working-age with moderate-to-severe TBI injured in 1995/1996, and hospitalized at the Trauma Referral Center in Eastern Norway. Functional status was measured by the Glasgow Outcome Scale-Extended (GOS-E). HRQL was assessed by the SF-36 questionnaire.The mean current-age was 40.8 years. The frequency of epilepsy was 19% and the depression rate 31%. A majority had good recovery (48%) or moderate disability (44%). Employment rate was 58%. Functional and employment status were associated with initial injury severity in contrast to HRQL. Study patients had significantly lower scores in all SF-36 dimensions when compared with the general Norwegian population.At 10-years follow-up, our study population is still in their most productive years and affected domains should be considered in long-term follow-up and intervention programs.