Evaluation of volumetric modulated arc therapy (VMAT) with Oncentra MasterPlan® for the treatment of head and neck cancer.
Evaluation of volumetric modulated arc therapy (VMAT) with Oncentra MasterPlan® for the treatment of head and neck cancer.
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DOI：
10.1186/1748-717x-5-110
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发表时间：
2010-11-22
期刊：
影响因子：
--
通讯作者：
Dobler B
中科院分区：
文献类型：
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作者：
Alvarez-Moret J;Pohl F;Koelbl O;Dobler B
几项对比研究表明，VMAT在减少治疗时间的同时，能够获得与IMRT相似或更好的计划质量。VMAT在多供应商环境中的体验有限。我们比较了VMAT和IMRT的计划质量和性能，并研究了不同用户可选参数的影响。比较调强放射治疗、单弧形VMAT和双弧形VMAT对四种不同头颈部肿瘤的诊断价值。对于VMAT，研究了不同的台架角度、间距和处理时间对平整质量的影响。对监测单位和治疗时间进行比较。IMRT和双圆弧VMAT获得了相似的平面图质量，而单圆弧无法提供可接受的平面图质量。增加控制点的数量并不能提高计划质量。双弧形VMAT的投放时间约为调强放疗投放时间的30%。双弧形VMAT是治疗头颈部肿瘤的一种快速、准确的技术。它采用了与IMRT相似的MU数量，但治疗时间大大减少，保持了与PTV和OAR备用的相似或更好的剂量一致性。
Several comparison studies have shown the capability of VMAT to achieve similar or better plan quality as IMRT, while reducing the treatment time. The experience of VMAT in a multi vendor environment is limited. We compared the plan quality and performance of VMAT to IMRT and we investigate the effects of varying various user-selectable parameters. IMRT, single arc VMAT and dual arc VMAT were compared for four different head-and-neck tumors. For VMAT, the effect of varying gantry angle spacing and treatment time on the plan quality was investigated. A comparison of monitor units and treatment time was performed. IMRT and dual arc VMAT achieved a similar plan quality, while single arc could not provide an acceptable plan quality. Increasing the number of control points does not improve the plan quality. Dual arc VMAT delivery time is about 30% of IMRT delivery time. Dual arc VMAT is a fast and accurate technique for the treatment of head and neck cancer. It applies similar number of MUs as IMRT, but the treatment time is strongly reduced, maintaining similar or better dose conformity to the PTV and OAR sparing.