Using the MEROPS Database for Proteolytic Enzymes and Their Inhibitors and Substrates.
Using the MEROPS Database for Proteolytic Enzymes and Their Inhibitors and Substrates.
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DOI：
10.1002/0471250953.bi0125s48
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发表时间：
2014-12-12
影响因子：
--
通讯作者：
Bateman, Alex
中科院分区：
文献类型：
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作者：
Rawlings, Neil D;Barrett, Alan J;Bateman, Alex
MEROPS 是蛋白水解酶及其抑制剂和底物的数据库。蛋白水解酶和蛋白抑制剂被组织成蛋白结构域家族。反过来，家庭又被组织成氏族。每个肽酶、抑制剂、家族和族都有相关的注释、多序列比对、系统发育树、文献参考和其他数据库的链接。还介绍了蛋白水解酶和抑制剂之间以及蛋白水解酶和底物之间的相互作用。 MEROPS 中的条目可通过万维网获得。本单元包含有关如何访问和利用 MEROPS 数据库中的信息的详细信息。介绍了远程和本地运行 MEROPS 的详细信息。
MEROPS is a database of proteolytic enzymes as well as their inhibitors and substrates. Proteolytic enzymes and protein inhibitors are organized into protein domain families. In turn, families are organized into clans. Each peptidase, inhibitor, family, and clan has associated annotation, a multiple sequence alignment, a phylogenetic tree, literature references, and links to other databases. Interactions between proteolytic enzymes and inhibitors and between proteolytic enzymes and substrates are also presented. The entries in MEROPS are available via the World Wide Web. This unit contains detailed information on how to access and utilize the information present in the MEROPS database. Details on running MEROPS both remotely and locally are presented.